DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtd and evi5

DIOPT Version :9

Sequence 1:	NP_001246928.1	Gene:	mtd / 45467	FlyBaseID:	FBgn0013576	Length:	1344	Species:	Drosophila melanogaster
Sequence 2:	XP_002933848.4	Gene:	evi5 / 733501	XenbaseID:	XB-GENE-983877	Length:	825	Species:	Xenopus tropicalis

Alignment Length:	524	Identity:	87/524 - (16%)
Similarity:	172/524 - (32%)	Gaps:	168/524 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 EDGSQSPRPVLQGLNTSYEGPQNDRQRRRRSSLQ-------TKLDRHRRKKMEYSNQRSLDSGMM 194
            |..|.:.|.:...:..:.|..:|...:|..::::       |||::......|..:||.|..
Frog   406 ESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEASTKLEQAHHTISELQHQRELHK--- 467

  Fly   195 CSESHS---------DLTNDSLAEGSGSFANRSRNGNDDEDDIIDPSHGEYFPREKRHSWWNIFV 250
            |:..:|         :|....|.|.....|.:     :.:|.|::        .|||    |..:
Frog   468 CNPRYSEEFVLQLETELVQARLKEAESHCAMK-----EMQDKILE--------IEKR----NASL 515

  Fly   251 PDNF------------KNRSRRASQDVSSLSRSVDNLAIPVRRSKSRSVDHGLAAPFDLDSLRSK 303
            ||..            |.|...|...:..:.:.:.||....:|..:|:..            |.|
Frog   516 PDEINVVRLQEELIAVKLREAEAVMALKEVKQQIKNLEEHWQRHLARTAG------------RWK 568

  Fly   304 VEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAARFDTTPSELTHL----------NRLN 358
            ...:..::::|                   :|.|.:|..|.....:||..:          |::|
Frog   569 DPPKKNTINEL-------------------QDELMTVRLREAERHAELREVRQRMMEMETQNQIN 614

  Fly   359 SSFIYPGQQLLVPDKSAKDDASSSSTH----DADGASLSGKSSPVERKLSGDESREKDILEGLR- 418
            |:      ||    :.|:.:.||..:.    .|....|..:.:..:||.:..|.:.|:.:..:|
Frog   615 SN------QL----RRAEQEVSSLQSKVQYLTAQNKGLQAQLNEAKRKQAEIECKNKEEVMAVRL 669

  Fly   419 -------PGSPKPGHIERVGGSSQQQQAEEEANKSD---------DPVITQRFLKINVRHITDGQ 467
                   ..:....||..:....::.:.:.:.|.||         |.::.   ||..::.:...:
Frog   670 READSIAAVAELQQHIAELEIQKEEGKIQGQLNNSDSSQYIRELKDQIVE---LKHEIKCLKSQK 731

  Fly   468 GVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLN 532
            |:        |:...||                |:.....::.:...||......|.|...:|
Frog   732 GL--------PDQPTFD----------------GIHIVNHIIGDDESFHSSDEEYVGGTLQEG-- 770

  Fly   533 SASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLC-SSTGRD 596
                   |.:.:..|           ...:..||..|:...|::..:|.|..|...:. ..||:.
Frog   771 -------KVQFHLHK-----------RHDKMALGPSGSDSSDSDTEALSIVTDSNGMVPKQTGKR 817

  Fly   597 GDAF 600
            .:::
Frog   818 TESY 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306	18/109 (17%)
		LysM	329..371	CDD:279777	11/51 (22%)
		TLDc	1182..1344	CDD:214733
evi5	XP_002933848.4	TBC	117..325	CDD:214540
evi5	XP_002933848.4	Smc	<350..694	CDD:224117	60/348 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910