DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtd and meak7

DIOPT Version :9

Sequence 1:	NP_001246928.1	Gene:	mtd / 45467	FlyBaseID:	FBgn0013576	Length:	1344	Species:	Drosophila melanogaster
Sequence 2:	NP_001038430.2	Gene:	meak7 / 561678	ZFINID:	ZDB-GENE-050419-140	Length:	450	Species:	Danio rerio

Alignment Length:	436	Identity:	108/436 - (24%)
Similarity:	168/436 - (38%)	Gaps:	106/436 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   952 GTFIRPHSSEGTSSSTK-----------LKEAKQAP----KLDYRSMVSMD-----------DKP 990
            |||.|.|.:..::|:.|           |...|.|.    |..::.:.|:|           .:.
Zfish    26 GTFDRLHGARSSASAGKTSKGLSLDMLQLTMGKMASESMIKRVFQGLHSIDPGVPLHPGDGVSRE 90

  Fly   991 ELFISVDKLIPRPA--RACLDPPLYLRLRMGKPIGKAIPLPT-SVMSYGKNKLRAEYWFSVPKNR 1052
            :|.|.:..::...|  ||    ||.|.:..|   .||....| .:..:.::.:.|.......|..
Zfish    91 QLLIFLADVLRGTAEERA----PLVLAMAEG---AKATVTTTEQIRGFMEDLVYAAVQTLAHKGH 148

  Fly  1053 VDELYRFINTWVKHLYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEEISDLTRES 1117
                   :..|.....|:      .|:|.:|:.|.        ..:.:....|:..:|:.|  |.
Zfish   149 -------LRAWQPERMGD------GAQGVKLLAEQ--------LTSELKPSDQNTCDIACL--ED 190

  Fly  1118 WELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSF----DLD--FPIP 1176
            | |.:.|....:             ||:|.||.|.:........:|.....|    ||.  ..:|
Zfish   191 W-LFRIPMMAMF-------------LELLIGEGLGVVLPSRPPPTLLPPCQFAPWTDLRCVLSLP 241

  Fly  1177 DLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLES--PVLIVIED 1239
            .|:..:.:|.|.|             ...|.::|||..||   .|..|.:...:|  |.:::::|
Zfish   242 LLMFLSPLLPEGH-------------SAPWRMLFSTKMHG---ESFTRLLGSCKSRGPTVLLVKD 290

  Fly  1240 TEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGEN---MYFIKGNM---ESLSIGA 1298
            |:.::||...|.|..|...|.|.....|:...|..:||..||.|   ||..:|..   ..|.:|.
Zfish   291 TKGHIFGGFASQSWEVKPQFQGDSRCFLFSVFPYMRVFTCTGYNDHYMYLNQGQQTMPNGLGMGG 355

  Fly  1299 GDGRFGLWLDGDLNQGRSQ---QCSTYGNEPLAPQEDFVIKTLECW 1341
            ..|.||||||.|...|.|:   :|:|||:..|:..|||.:.|||.|
Zfish   356 QHGYFGLWLDYDFGHGHSRARPRCTTYGSPQLSADEDFKLDTLEVW 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306
		LysM	329..371	CDD:279777
		TLDc	1182..1344	CDD:214733	56/171 (33%)
meak7	NP_001038430.2	TLDc	237..404	CDD:214733	58/181 (32%)
meak7	NP_001038430.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	430..450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910