Protein Alignment mtd and Ncoa7

DIOPT Version :9

• Sequence 1: NP_001246928.1
• Gene: mtd / 45467
• FlyBaseID: FBgn0013576
• Length: 1344
• Species: Drosophila melanogaster
• Sequence 2: XP_038955206.1
• Gene: Ncoa7 / 498995
• RGDID: 1566426
• Length: 977
• Species: Rattus norvegicus
• Alignment Length: 1229
• Identity: 356/1229 - (28%)
• Similarity: 540/1229 - (43%)
• Gaps: 312/1229 - (25%)

  Fly   170 QTKLDRHRRKKMEYSNQRSL-DSGMMCSESHSDLTNDSLAEGSGSFANRSR-------------- 219
            :.|.:...||:..::..:.| ......:||:.   |.|..|.:.||.:|||
  Rat     5 EEKKEPKERKQSYFARYKYLIIQNTAATESNQ---NRSPLEHAKSFPSRSRLKKKKQAKQNAEIV 66

  Fly   220 ------NGNDDEDDIIDPSHGEYFPREKRHSWWNIFVPDNFKNRSRRASQDVSSLSRSVDNLAIP 278
                  :|.||       ||.....::|             .|.:....|......:..:|....
  Rat    67 SAARSHSGKDD-------SHSVILEQDK-------------SNIAAEGDQSTDEKKKRKNNQLKE 111

  Fly   279 VRRSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAAR 343
            :||.:       |...::.|..:||...:.|.  |:..||..    .|:.||.|::|||.|||.:
  Rat   112 IRRME-------LKRYYNADDNQSKSHDKKEK--KMVVQKPQ----GTLEYTAGSQDTLNSVALK 163

  Fly   344 FDTTPSELTHLNRLNSSFIYPGQQLLVPDKSAKDDA--SSSSTHDADGASLSGKSSPVERKLSGD 406
            |:.||:.|..||:|.:..|.|||.|.|||.:.....  .||||   .||::|..||..|.    |
  Rat   164 FNVTPNRLVELNKLFTHTIVPGQVLFVPDANIPSSTLRLSSST---PGATVSPSSSDAEY----D 221

  Fly   407 ESREKDIL-EGLRPGSPKPGHIERVGGSSQQQQAEEEANKSDDPVITQRFLKINVRHITDGQGVV 470
            :..:.|:. :.|:|       ||||..|:.::         |:|.:. :|||:|.|:.|||:|||
  Rat   222 KLPDADLARKALKP-------IERVLSSTSEE---------DEPGVV-KFLKMNCRYFTDGKGVV 269

  Fly   471 GGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLNSAS 535
            |||::||||.:||||:.|||||||:|.|.||:|.|||.||:.|:::||:||::.
  Rat   270 GGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIK----------- 323

  Fly   536 GDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLCSSTGRDGDAF 600
             ||                   ||..           |..::..|....:.|.|.|.  :|.:.|
  Rat   324 -DA-------------------LPSD-----------LPRDVCPLYRPGEWEDLASE--KDINPF 355

  Fly   601 P--KAFDRERVEDSSMEAKDSAKTDALDDEDKKAGLGLSSTRSTLEERRKSLLDHHWAIPSKDRS 663
            .  |:.::|:      ..::..:|.|||  .|..|....||     ||.::             .
  Rat   356 SKFKSINKEK------RQQNGERTLALD--VKSVGSPEEST-----ERMRT-------------R 394

  Fly   664 SEDEGDNES----NVTVDSGARVQDPHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSG 724
            :|...|:||    |:....|...:.|       |...||:.|.:..||....|..:.::    ..
  Rat   395 TEPPDDSESWKLKNLEYSRGTASEFP-------SVTQLSKGPSSVCAALEPTAKENRLL----GD 448

  Fly   725 IDLEHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPR 789
            .|...||:||.|.  .||:|..:......|..:|   .||          |:||:.....|....
  Rat   449 EDFVDLEELSSQP--GSGMDKGDARKECLPYDQK---KDA----------PQTIMSAKKGEEQSA 498

  Fly   790 STILGQSLDAGTGGA----GGVRKKTSSVSFSVDDEAAQQAQAQSAALAVTDKQADK-------- 842
            ..:.|...||...||    .|.::..:.   .||.::......:.:.|:: .:..||
  Rat   499 PDVTGTESDAELKGALDSETGEKQDEAP---EVDKQSGSPENWRESTLSI-HEDLDKVKLIEFYL 559

  Fly   843 -KNKMLKRLSYPLTWVEGLTGEGGAVPPGGVG---SGSLNKSGDTDSAPNTGDSNQSVFSKVFSS 903
             |||...:||..:  ::....|..::.|.|:.   |.||.::|  ||.|.:            ..
  Rat   560 NKNKEGSQLSENV--LKSELSERKSIEPDGIDITLSSSLPQAG--DSPPES------------HK 608

  Fly   904 SPITLVSELGGNLFSKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTK 968
            .|.||..:             .||:|.|.|.|   .:|..:|..:.::           .|..:.
  Rat   609 EPGTLCVK-------------GGGTPPPKLHP---SAEETVTNNKEAL-----------DSLESS 646

  Fly   969 LKEAKQAPKLDYRSMVSMDDKPELFISVDKLIPRPARACLDPPLYLRLRMGKPIGK--AIPLPTS 1031
            |.:..|..::|.||.:.:.....:.:.::.::|........||::|.:::|||:.|  |....|.
  Rat   647 LDKLCQGAQMDNRSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHSTTM 711

  Fly  1032 VMSYGKNKLRAEYWFSVPKNRVDELYRFINTWVKHLYGELDEEQIKARGFELIQEDTEWTKSGTT 1096
            |..|||.:.:.||||:||:.|||.||.|...|...:||:..:||    ||.::::
  Rat   712 VQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQ----GFVVVEK---------- 762

  Fly  1097 KAGMGGGSQDGEEI-------SDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMS 1154
                       ||:       |:.|.:|||:|....||..|  .|.|:....:.|..|
  Rat   763 -----------EELTMIDNFFSEPTTKSWEIITVEEAKRRK--STCSYYEEEEEEEEG------- 807

  Fly  1155 TDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFAL 1219
                                :|.|...:.:|...|.|:|...||||.:||.|.|.:||.:||.:|
  Rat   808 --------------------LPILQSHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSL 852

  Fly  1220 NSLYRKMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGENM 1284
            .:||||.|.|:||||:||:|.::.:|||..:.....|||:|||||:.||.|:|:||||.|:|||.
  Rat   853 KTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFRFSDHYYGTGETFLYTFSPNFKVFKWSGENS 917

  Fly  1285 YFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQEDFVIKTLECWAF 1343
            |||.|::.||.:|.|.||||||||.||..|||..|||:.|:.|:.:|||:::.||.|.|
  Rat   918 YFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTF 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306	33/99 (33%)
		LysM	329..371	CDD:279777	21/41 (51%)
		TLDc	1182..1344	CDD:214733	86/162 (53%)
Ncoa7	XP_038955206.1	LysM	149..191	CDD:396179	21/41 (51%)
		TLDc	815..977	CDD:214733	86/162 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3017
eggNOG	1	0.900	-	-		E1_COG5142
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	402	1.000	Inparanoid score	I1861
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384247at33208
OrthoFinder	1	1.000	-	-		FOG0001020
OrthoInspector	1	1.000	-	-		otm45838
orthoMCL	1	0.900	-	-		OOG6_100646
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2069
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730