DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtd and sky

DIOPT Version :9

Sequence 1:	NP_001246928.1	Gene:	mtd / 45467	FlyBaseID:	FBgn0013576	Length:	1344	Species:	Drosophila melanogaster
Sequence 2:	NP_001260649.1	Gene:	sky / 35359	FlyBaseID:	FBgn0032901	Length:	607	Species:	Drosophila melanogaster

Alignment Length:	261	Identity:	73/261 - (27%)
Similarity:	124/261 - (47%)	Gaps:	39/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly  1111 SDLTRESWELIKA------PFAKTYKIIKTASHAASHDLEMLGGEV---LSMSTDEYRKTSLFAT 1166
            |.||..|.:|||:      |.:::...|:..||..: ..|.|..|.   |...:..:|..::..
  Fly   357 SVLTSGSKQLIKSRSSDNLPTSQSQVNIQMMSHTLT-IREKLHSESCRNLGEKSPGHRAIAMGV- 419

  Fly  1167 GSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLES 1231
                  :||.:|  |::....|....|.|.||.|...|...|:::|.:||.:|.:.|.::.:.|
  Fly   420 ------YPIHNL--KSQACKNEDLFTLWSWLPVRITMYQPVLLYTTEEHGCSLTTFYVRVEQHE- 475

  Fly  1232 PVLIVIEDTEHNVFGALTSC---SLHVSDH------FYGTGESLLYKFNPSFKVFHWTG------ 1281
            |.|::|:...:.||||..|.   ..:|.|.      ::||||:.|:...|....:.|.|
  Fly   476 PTLLMIKTCNNEVFGAYCSSRWFERNVKDDKGQRQAYFGTGETFLFSLYPERAKYPWVGIEGDKD 540

  Fly  1282 ---ENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQEDFVIKTLECWAF 1343
               .:..|:..:.:.::||.|:|: .:|:|.::..|::..|.|:.|.||.|..||.|:.||.:.|
  Fly   541 LGHSSELFMAADSKMITIGGGEGQ-AIWMDENIRFGKTDSCKTFNNPPLCPSGDFEIRVLEVYGF 604

  Fly  1344 V 1344
            |
  Fly   605 V 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306
		LysM	329..371	CDD:279777
		TLDc	1182..1344	CDD:214733	51/179 (28%)
sky	NP_001260649.1	RabGAP-TBC	82..293	CDD:382990
sky	NP_001260649.1	TLDc	431..605	CDD:214733	51/175 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I2657
eggNOG	1	0.900	-	-		E1_COG5142
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47037
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.810