DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtd and CG4658

DIOPT Version :9

Sequence 1:	NP_001246928.1	Gene:	mtd / 45467	FlyBaseID:	FBgn0013576	Length:	1344	Species:	Drosophila melanogaster
Sequence 2:	NP_001285789.1	Gene:	CG4658 / 34325	FlyBaseID:	FBgn0032170	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	95/533 - (17%)
Similarity:	179/533 - (33%)	Gaps:	150/533 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   795 QSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALA-VTDK------QADKKNKMLKRLSY 852
            :|.||...|...|....:::..:    .||.:..:||:.| ||:|      ..:|..::|:..:.
  Fly    30 KSSDASHNGVSDVGGSHNNLKVT----QAQGSMTRSASGADVTEKYLTQLVPVEKLAEILREQTS 90

  Fly   853 PLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLF 917
            ....:.|:..:                                    ||.|......::||..||
  Fly    91 SKLGINGIVAD------------------------------------VFVSQVFPQYADLGQRLF 119

  Fly   918 SKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRS 982
            :...|....          :|...|.:.: |.....|:      |....:|..|.       |..
  Fly   120 NLMHSNSKA----------TTKHLGAVAF-RQQCERFL------GIMDDSKTLEC-------YIK 160

  Fly   983 MVSMDDKPELFISVDKL-IPRPARACLDPPLYLRLRMGKPIGKAIPLPTSVMSYGK--------- 1037
            |.:.::.|:   .:||. :.|....|....:       :..|.|:..|....::|.
  Fly   161 MYAQEENPD---QIDKTGVTRLLHICYTIAM-------QHSGNAVLCPAINRTFGSVTKSIFLCH 215

  Fly  1038 NKLRAEY---WFSVPKNRVDELYRFINTWVKH----LYGELDEEQIKARGFELIQEDTEWTKSGT 1095
            :.:...|   ||   :..:..|...::.:..|    .|..| |:|.::.|.||.....|.....|
  Fly   216 DSMSLGYVCRWF---EQNLMRLVLLVHKYCVHTLSTAYRGL-EQQNQSCGIELQTPVLEQRNPFT 276

  Fly  1096 TKAGMGGGS-QDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYR 1159
            ......||| ::.:.:..|: ::| |:.......|...:|.:..|:.     |...:|.||
  Fly   277 DTTDFSGGSTREMDSLMPLS-QAW-LLAGALPPLYSKPQTVTPPATK-----GNNNVSAST---- 330

  Fly  1160 KTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYR 1224
            ...:|                         ::|| |.:|:.     |:|::::::||...|....
  Fly   331 AVQIF-------------------------KDKL-SMMPSH-----WTLLYNSNEHGVGANRFLH 364

  Fly  1225 KMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGE-SLLYKFNPSFKVFHWTGENMYF-- 1286
            .:.....|.|:::...:...: .:.|.|.....|.:..|| |.:.:..|.|.:.......:|.
  Fly   365 HVLGYRGPTLVLLHTKDEQTY-CVASPSEWKETHLFVGGEGSCVIQLLPKFVILEKKPNILYLNT 428

  Fly  1287 -IKGNMESLSIGA 1298
             |:|..:.|..||
  Fly   429 SIRGYPKGLRAGA 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306
		LysM	329..371	CDD:279777
		TLDc	1182..1344	CDD:214733	25/121 (21%)
CG4658	NP_001285789.1	TLDc	327..475	CDD:214733	29/151 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23354
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010