Protein Alignment mtd and Tbc1d9

DIOPT Version :9

• Sequence 1: NP_001246928.1
• Gene: mtd / 45467
• FlyBaseID: FBgn0013576
• Length: 1344
• Species: Drosophila melanogaster
• Sequence 2: XP_006255308.1
• Gene: Tbc1d9 / 304645
• RGDID: 1308221
• Length: 1262
• Species: Rattus norvegicus
• Alignment Length: 1208
• Identity: 226/1208 - (18%)
• Similarity: 393/1208 - (32%)
• Gaps: 423/1208 - (35%)

  Fly   155 EGPQNDR--------QRRRRSSLQTKLDRHRRKKMEYSNQRSL-----DSGMMCSESHSDLTNDS 206
            ||.:.||        ..::.|:|:..||. |.|...|   |:|     |..:   :.|:|.|
  Rat   260 EGFEQDRSLPKLKKKSPKKVSALKRDLDA-RAKSERY---RALFRLPKDEKL---DGHTDCT--- 314

  Fly   207 LAEGSGSFANRSRNGNDDEDDIIDPSHGEYFPREKRHSWWNIFVPDNFKNRSRRASQDVSSLSRS 271
                                        .:.|..|.|....:||..|:        ...:|...:
  Rat   315 ----------------------------LWTPFNKMHILGQMFVSTNY--------ICFTSKEEN 343

  Fly   272 VDNLAIPVR------RSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYT 330
            :.:|.||:|      ::.|.||   |.:|..: |.|:::...|.::.
  Rat   344 LCSLIIPLREVTIVEKADSCSV---LPSPLSI-STRNRMTFLFANLK------------------ 386

  Fly   331 VGNRDTLTSVAARF--DTTPSELTHLNRLNSSF----------IYPGQQLLVPDKSAKDDASSSS 383
              :||.|....:.|  .||       :|:.|.|          :|.....||   |:....|:||
  Rat   387 --DRDFLVQRISDFLQQTT-------SRIYSEFSGSCNSSDDEVYSRPSSLV---SSSPQRSTSS 439

  Fly   384 THDADGA---SLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIERVGGSSQQQQAEEEANK 445
              ||||.   :|:|.|.|         :..:.::...|..||                  ||.|
  Rat   440 --DADGERPFNLNGNSVP---------TATQTLMTMYRRRSP------------------EEFN- 474

  Fly   446 SDDPVITQRFLKINV--RHITD-GQGVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPME 507
               |.:.:.|||...  .|..: |||:           .|:....:..||::..||.  :...:.
  Rat   475 ---PKLAKEFLKEQAWKIHFAEYGQGI-----------CMYRTEKTRELVLKGIPER--MRGELW 523

  Fly   508 LVVNAAIFHDIAHM-----RVAGGAGQGLNSASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGE 567
            |:::.||.....|.     .|....|: .|.|:.:.|:            :..:.|||..:...|
  Rat   524 LLLSGAINEKATHPGYYEDLVEKSMGK-YNLATEEIER------------DLHRSLPEHPAFQNE 575

  Fly   568 DGNKRL----------DAEIGSLEIADDQESLCSSTGRDGDAF-----------PKAFDRE---- 607
            .|...|          :..||..:..:...|:.....::.:||           |..::..
  Rat   576 MGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGA 640

  Fly   608 RVEDSSME--AKDSAKT--DALDDEDKKAGLGLSSTRS-----TLEERRKSLLDHHWAIPSKDRS 663
            .|:....|  |:|....  |.:.|      ||:.||.|     ||   ..|::....|:
  Rat   641 LVDQGVFEELARDYVPQLYDCMQD------LGVISTISLSWFLTL---FLSVMPFESAV------ 690

  Fly   664 SEDEGDNESNVTVD----SGARVQDPHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSG 724
                      |.||    .|.:|                   :...|.|...|....::.....|
  Rat   691 ----------VVVDCFFYEGIKV-------------------IFQLALAVLDANVDKLLGCKDDG 726

  Fly   725 IDL----EHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTV--YSDADI--VLSSDW-----VPPK 776
            ..:    .:|:.::.:   ||.:   .|:|::..:....|  |...||  ::.:.:     :...
  Rat   727 EAMTVLGRYLDSVTNK---DSTL---PPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRAD 785

  Fly   777 TIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALAV-----T 836
            .|....|.:   |..:: |:|: .|.....||...:..||::|:.....|..::..|..     :
  Rat   786 LIEQMRFKQ---RLKVI-QTLE-DTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGS 845

  Fly   837 DKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGVGSGS----------LNKSGDTDSAPNTGD 891
            ....|:.:..|..|.......|...|....:.|...|:.|          |:::||:
  Rat   846 SNAPDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDS-------- 902

  Fly   892 SNQSVFSKVFSSSPITLVSELGGNLFSK-----------TPS--EDSGGSP-------VPPLTPH 936
               .:..:.|.|.   |.:...|:|..|           .||  :|...|.       ...:||.
  Rat   903 ---LINFREFVSG---LSAACHGDLTEKLKLLYKMHVLPEPSCDQDEPDSAFEATQYFFEDITPE 961

  Fly   937 STHSEGHMTYGRSSIGT-FI----------RPHSSEG--------TSSSTKLKEAKQAPKLDY-- 980
            .||..|..:.|:.|... |:          |.:|.|.        ..:.:|.|.||..|||:.
  Rat   962 CTHVVGLDSRGKQSADEGFVTVSLKQDRGKRANSQENRHYLKLWTAENKSKSKNAKDLPKLNQGQ 1026

  Fly   981 -----RSMVSM--DDKPE------------LFISVDKL----IPRPARACLDPPLYLRLRMGKPI 1022
                 ::|.:|  :|..|            |.:.:.::    |.:||:....|        |.|.
  Rat  1027 FIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPAKEDAVP--------GPPC 1083

  Fly  1023 GKAIPLPTSVMSYGKNKLRAEYWFSVPKNRVDELYRFINT--WVKHLYGELDEEQIKARGFELIQ 1085
            .:|||                 ....||....:.|...:|  ....|.|:.:|..:..:..::..
  Rat  1084 SQAIP-----------------GMLFPKKGSSQSYVVESTDPLPASLAGDREEHSLGGQMEDIKL 1131

  Fly  1086 EDTEWTKSGTTKAGMGGGSQDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASH-DLEMLGGE 1149
            ||:....:|.. :.|.....|.::.|.::             :|.::...||.... ..|.:|.:
  Rat  1132 EDSSPRDNGAC-SSMLISDDDTKDDSSMS-------------SYSVLSAGSHEEDKLHCEDIGED 1182

  Fly  1150 VLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTE 1187
            .:.:.:.:.| .:|..:.|.|.|:.|........:|||
  Rat  1183 TVLVRSSQGR-AALPRSSSLDRDWAITFEQFLASLLTE 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306	23/117 (20%)
		LysM	329..371	CDD:279777	11/53 (21%)
		TLDc	1182..1344	CDD:214733	3/6 (50%)
Tbc1d9	XP_006255308.1	PH-GRAM1_TCB1D9_TCB1D9B	157..255	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	304..399	CDD:270161	26/160 (16%)
		TBC	510..720	CDD:214540	47/268 (18%)
		EFh	<891..921	CDD:298682	7/43 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910