Protein Alignment mtd and Tbc1d10a

DIOPT Version :9

• Sequence 1: NP_001246928.1
• Gene: mtd / 45467
• FlyBaseID: FBgn0013576
• Length: 1344
• Species: Drosophila melanogaster
• Sequence 2: NP_598784.1
• Gene: Tbc1d10a / 103724
• MGIID: 2144164
• Length: 500
• Species: Mus musculus
• Alignment Length: 578
• Identity: 110/578 - (19%)
• Similarity: 176/578 - (30%)
• Gaps: 193/578 - (33%)

  Fly   375 AKDDASSSSTHDADGASLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIER--------VG 431
            ||....:.....|.|.||||..   |....|.::...|.|..|...|...|..||        ||
Mouse     2 AKSSRENGPREPAAGGSLSGTR---ESLAQGPDAATADELSSLGSDSEANGFAERRIDKFGFIVG 63

  Fly   432 GSSQQQQAEE---------EANKSD-----DPVITQRFLKINVRHITDG----------QGVVGG 472
            ....:...||         |:...|     |..:.::..||.:| ...|          |.:.||
Mouse    64 SQGAEGALEEVPLEVLRQRESKWLDMLNNWDKWMAKKHKKIRLR-CQKGIPPSLRGRAWQYLSGG 127

  Fly   473 VLLVTPNAVMFDP---NVSDPLVIEHGPESYGVIAPMELVVNAAI-----FHDIAHMRVAGGAGQ 529
            .:.:..|...||.   :..||..::              |:...:     ||::...|  ||.||
Mouse   128 KVKLQQNPGKFDELDMSPGDPKWLD--------------VIERDLHRQFPFHEMFVSR--GGHGQ 176

  Fly   530 G-----LNSASGDAEKPEIYY---PKPV----------------LVEEDSKELPEQQSLLGEDGN 570
            .     |.:.:  ..:||..|   ..|:                ||:...|.||...|
Mouse   177 QDLFRVLKAYT--LYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQVCEKYLPGYYS------- 232

  Fly   571 KRLDAEIGSLEIADDQESLCSSTGRDGDAFPKAFDRERVEDSSMEAK----DSAKT--------- 622
            ::|:|      |..|.|.|.|...:......|...|::::......:    ..|:|
Mouse   233 EKLEA------IQLDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWFMCAFARTLPWSSVLRV 291

  Fly   623 -DALDDEDKKA--GLGLSSTRSTLEERRKSLLDHHWAIPSKDRSSEDEGDNESNVTVDSGARVQD 684
             |....|..|.  .:||            .||.|....|.|.::.:.:.:....:...|...:|:
Mouse   292 WDMFFCEGVKIIFRVGL------------VLLKHALGSPEKLKACQGQYETIEQLRSLSPKIMQE 344

  Fly   685 PHSANSSVSGVPLSQPPVAAAAAAAAVAPASAVVPLPPSGIDLEHLEQLSKQSCYDSGIDIREPV 749
            .......:.                        :|:....|:.|||.||.:.......::.|.
Mouse   345 AFLVQEVIE------------------------LPVTERQIEREHLIQLRRWQETRGELECRS-- 383

  Fly   750 PNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSV 814
                 :|:   ...|..:|.::..|...:.|:.....||.:.:|.
Mouse   384 -----LPR---MHGAKAILDAEPGPRPALQPSPSIRLPPDAALLS-------------------- 420

  Fly   815 SFSVDDEAAQQAQAQSAALAVTDKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGV 872
            |.:...:.||:.|.::...|..||            |..|:....:|..|.|.||.||
Mouse   421 SKAKPHKQAQKEQKRTKTSAQLDK------------SPGLSQATVVTAAGDACPPQGV 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306
		LysM	329..371	CDD:279777
		TLDc	1182..1344	CDD:214733
Tbc1d10a	NP_598784.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		13/45 (29%)
		TBC	110..313	CDD:214540	46/245 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..415		3/18 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	420..500		16/79 (20%)
		Binding to the PDZ domain of EBP50. /evidence=ECO:0000250	497..500

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910