Protein Alignment Pex1 and RIX7

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_013066.1
• Gene: RIX7 / 850625
• SGDID: S000003957
• Length: 837
• Species: Saccharomyces cerevisiae
• Alignment Length: 916
• Identity: 223/916 - (24%)
• Similarity: 380/916 - (41%)
• Gaps: 203/916 - (22%)

  Fly   201 ELTEKLTPLTHSSTVSNVKNTIQRNKRQDHMERLKKDLRRESSRSFEFRVIRGLWREQAQESDVF 265
            ::..|...|| ||..:.:.:.|.|...:..::| |:.||:||...      .|...|..::.|:|
Yeast     3 KVKSKKNSLT-SSLDNKIVDLIYRLLEEKTLDR-KRSLRQESQGE------EGENNEGEEDEDIF 59

  Fly   266 VNGKHLPEFFDLDLFYCMHTAADKDYYVRVRTVEDDIEDDLPETIHPSIELNANLMKLLGIKELE 330
            .:     .||..||     ||.:...:.                          |.|.|.::.::
Yeast    60 ES-----MFFAKDL-----TAGEIFTFC--------------------------LTKDLSLQRVK 88

  Fly   331 RVVLRPKT--TVVNFVEKIEL--------FANKKTHYKIMEN--AFKRFVIERTQHKPMLFNQ-- 381
            :|||: ||  .::..|.:.||        :.|::.....:|.  |.|..:|||..::   .|:
Yeast    89 KVVLQ-KTIDRMLKDVIESELEEFGSYPGYNNEEEEKPSLEEELAKKNMMIERDTNE---MNKRI 149

  Fly   382 -----------EEVVRLEDDLLVTVGILPEHFR--YCVVDAQFLKESKIYAADLVRPVGEIIKEE 433
                       |.:...:|.....|....:..:  .|.|..|.:||                 :.
Yeast   150 TSTWSKSGSVSESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKE-----------------DR 197

  Fly   434 TPPTSPLSVQDLIQLPEYDKIVDQVVQELRMNLC---LSADNSVMRQCNVLLAGASGTGKTVLVE 495
            :||.|.|.     .|...|.:|.|:::.:.:.:.   :.....|.....|||.|..|.|||.:..
Yeast   198 SPPNSSLK-----SLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIAN 257

  Fly   496 RILDQLSRKPDYCHFEFFHGSRSKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLA--HAAG 558
            .:..:| :.|   .......|...|...|| :|.:|::|......||.:|..:.:|.:.  ...|
Yeast   258 ALAGEL-QVP---FISISAPSVVSGMSGES-EKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGG 317

  Fly   559 EQSSQDGEYYNRMADTVYQLIVQYTTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLE 623
            .|...:.....::..::.:|.::.|....:.:|...|...:|:..|.. .||...:....:||
Yeast   318 AQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRR-AGRFDREICLNVPN-- 379

  Fly   624 RADREIILRELCSHINVAKDLDLVKFSNLTEGYRKCDLVQFVERA-------IFYAYRISKTQPL 681
            ...|..||:::..::.:...:|..|.:.||.|:...||...|..|       ||..|...|:.|.
Yeast   380 EVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKSTPT 444

  Fly   682 LTNDQLIESLEHTNSYCLQGIQSN-QRTGNDADANEMRV-------------------------- 719
            ...|...:::|...:  ..|.:|: :.|.|..|...:.|
Yeast   445 TATDSSEDNMEIDET--ANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYED 507

  Fly   720 --EELPGLESV----------------VGVLEEV-------LMWPSRYPTIFNASPLRNQAGVLL 759
              :.||.::..                ||.|:.|       ::.|.:.|.::....:....||||
Yeast   508 FLKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLL 572

  Fly   760 YGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDS 824
            :||||.|||.|...:|.......||:||||||.||:|:||.::|.:|.|||::.|||:||||.|:
Yeast   573 WGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDA 637

  Fly   825 LAPKRGHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPD 889
            |.|:|....:..:.||||.|||||||:...:|:.||.||:||:::|||:||.||:|:.:...||:
Yeast   638 LVPRRDTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLFIELPN 702

  Fly   890 APARVRIFEALSST----LSLDECVDFDWFA--GKTANYTGADIQSILTSANMAAVKEALAQFGH 948
            ...::.|.:.|:.:    ||.|  |||:...  .|..|::|||:.:::..:::.|:|...  |..
Yeast   703 TEEKLDIIKTLTKSHGTPLSSD--VDFEEIIRNEKCNNFSGADLAALVRESSVLALKRKF--FQS 763

  Fly   949 EKL--------------------AKKISLKQKHLIESFQTTRPSLSASDVAKYHRTYAR--FTNK 991
            |::                    .::|.:.......:.:..:||:|..|..||.|...:  .|.:
Yeast   764 EEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFRSALRKIKPSVSDKDRLKYDRLNKKMGLTEE 828

  Fly   992 EKTSRE 997
            .|.:.|
Yeast   829 MKDAEE 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	182/722 (25%)
		RecA-like_PEX1_r2	728..885	CDD:410934	74/179 (41%)
RIX7	NP_013066.1	CDC48	<192..824	CDD:273521	172/667 (26%)