Protein Alignment Pex1 and ATAD1

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_116199.2
• Gene: ATAD1 / 84896
• HGNCID: 25903
• Length: 361
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 75/274 - (27%)
• Similarity: 130/274 - (47%)
• Gaps: 22/274 - (8%)

  Fly   713 DANEMRV--EELPGLESVVGVLEEVLMWPSRYPTIF-NASPLRNQAGVLLYGPPGTGKTYLVSQL 774
            |...|.|  .::.||:.|:..|::.::.|.:...:| |:..|:...|||||||||.|||.:....
Human    82 DPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146

  Fly   775 ATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRG---HDSTGV 836
            |.....|.|:::...|..|:.|:|::....:|:.|...:|.::|.||.||....|.   |::|.:
Human   147 AKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAM 211

  Fly   837 TDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALS 901
            .......|...||.....| |.|:.||:||:.||.|::|  |:........|....|..|.:.:.
Human   212 MKAQFMSLWDGLDTDHSCQ-VIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKLIL 273

  Fly   902 STLSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKE---ALAQFGHEK----------LAK 953
            ...::|..||....|.:|..::|:|::.:...|.:..|:|   :.::..|::          |.:
Human   274 KNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHR 338

  Fly   954 KISLKQKHLIESFQ 967
            .|...:|....:||
Human   339 AIEKMKKSKDAAFQ 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	75/274 (27%)
		RecA-like_PEX1_r2	728..885	CDD:410934	51/160 (32%)
ATAD1	NP_116199.2	SpoVK	4..344	CDD:440232	72/264 (27%)
		RecA-like_ATAD1	92..257	CDD:410928	53/167 (32%)