Protein Alignment Pex1 and pex6

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_001332652.6
• Gene: pex6 / 792998
• ZFINID: ZDB-GENE-081104-252
• Length: 1071
• Species: Danio rerio
• Alignment Length: 1005
• Identity: 244/1005 - (24%)
• Similarity: 416/1005 - (41%)
• Gaps: 219/1005 - (21%)

  Fly    83 CALIADVLNLRSVHVT-------PVSSKDWEIIELSTEKISGSVLEQTRIVN-STQILIVWINKS 139
            |.:::|..:|...|.:       |.|:............:|.|:|.....:: |..|..:.....
Zfish   190 CVVLSDCRDLDVFHSSTAALCRPPNSAPFVSDFAQCANSLSSSLLSSRVCLDFSAFIEALECRLD 254

  Fly   140 MQVALTVDRLKP-----HMNYGRIDHNTELVVAPNLYKGLTNGTSNG--VIEENTKLSRSKTTAQ 197
            ::|..|.|.|||     .:|...:|.:..:.|:.:|...|  |..||  ||            |.
Zfish   255 VRVVETSDLLKPGGIVSALNDEEVDVDCCVFVSRSLLVKL--GVFNGEWVI------------AS 305

  Fly   198 VKDELTEKLTPLTHSSTVSNVK-NTIQRNKR--QDHMERLKK-DLRRESSRSFE---------FR 249
            |..|.. |.:|...|..:...: ..||..||  :.|:..:|. |..|...:...         |.
Zfish   306 VPGEKV-KRSPAVQSPVLGEGEGGKIQHQKRAGRVHLVCIKAFDTGRREDKDVAVGFVSVVQWFN 369

  Fly   250 VIRGL-------------WREQAQESD-------------VFVNGKHL-----PEFFDLDLF-YC 282
            :..|:             |.:.:..:|             .|....|:     |::..|.|| ..
Zfish   370 LSDGMAVPVGNKTIKIKRWNKASSHTDPQVSASACRCSSPPFAKELHIETIISPDYSALGLFSSV 434

  Fly   283 MHTAADKDYYVRVRTVEDDIEDDLPETIHPSIELNANLMKLLGIKELERVVLRPKTTVVNF-VEK 346
            :||     ::.:.|.|:......:|...||.:..|.:          |.|:..|   |:.| |::
Zfish   435 LHT-----HFSKPRLVQQGNILAVPTQGHPELMENGS----------EGVLRWP---VLYFRVKQ 481

  Fly   347 IELFANKKTHYK--IMENAFKRFVIERTQHKPMLFNQEEVVRLEDDLLVTVGILPEHFRYCVVDA 409
            ...|::::....  :.:::.....:..:.|.                |....:|||...:.:
Zfish   482 ACGFSSEEEEASSYLADSSHTSLYMGGSAHS----------------LCPYSVLPEASSFWI--- 527

  Fly   410 QFLKESKIYAADLVRPVGEIIKEETPPTSPLSVQDLIQLPEYDKIVDQVVQELRMNLCLSADNSV 474
                                  ..:||....:|:.||      .|:...:.|..:.|
Zfish   528 ----------------------SLSPPGLSSTVEKLI------TIIQPHLNESTLIL-------- 556

  Fly   475 MRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRSKGRKTESI----------QKD 529
            .|.|::||.|.:|:||...|..:..:|       |....        |.:.:          :..
Zfish   557 KRGCSILLMGPNGSGKFTAVRAVSRRL-------HLHLI--------KVDCVTLCADTAAASEAK 606

  Fly   530 LRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQYTTNNAIAVIATV 594
            ::::|.....|.|.:::|.||.:|.     ||....|...|:|.|:.|||.  ..:.::.|:.:|
Zfish   607 IKSVFERAELHHPCLLLLRNLQLLG-----QSRDGAETDCRVAATLCQLIA--AVHTSVVVVGSV 664

  Fly   595 NELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILRELCSHINVAKDLDLVKFSNLTEGYRKC 659
            :....|...:.:     .|.....:.:|....|..:|..|...:.:.||::|.:.:..|.|:...
Zfish   665 SSQHELPSDVMA-----AFVHQVAIESLSEDQRRTVLSSLSEDLLLGKDVNLGRIAKQTAGFVLG 724

  Fly   660 DLVQFVERAIFYAYR--ISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQRTGNDA-----DANEM 717
            ||...:..|...|:|  :....|...::|..|.|      |:.|:.......:.|     :|:..
Zfish   725 DLCALLTNAGKAAHRRLVETYFPEAVSEQEEEDL------CVSGVSVTSEDFSAALDVLQEAHSQ 783

  Fly   718 RV----------EELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVS 772
            .:          :::.||:.|...:.:.:..|..:|.:.:.. || ::|:|||||||||||.|..
Zfish   784 AIGAPKIPAVSWQDVGGLQQVKKEILDTIQLPLEHPELLSLG-LR-RSGLLLYGPPGTGKTLLAK 846

  Fly   773 QLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGH--DSTG 835
            .:||...:..:|||||||:..|:||||||:|.:|::||||.||::||||.|||||.|||  ||.|
Zfish   847 AVATECTMTFLSVKGPELINMYVGQSEENIRQVFSKARSAAPCIIFFDELDSLAPNRGHSGDSGG 911

  Fly   836 VTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPL-PDAPARVRIFEA 899
            |.||||:|||.||||:.....|.||.||:||:|||.:|||.||.|:||...: .|..:::::.:|
Zfish   912 VMDRVVSQLLAELDGLHSSGDVFVIGATNRPDLLDQSLLRPGRFDKLVYVGINEDRESQLQVLKA 976

  Fly   900 LSSTLSLDECVDF-DWFAGKTANYTGADIQSILTSANMAAVKEALAQF--GHEKLAKKISLKQKH 961
            :.....:|..|.. |.........||||:.|:.:.|.|.|||..:::.  |.:.....::|..:.
Zfish   977 ILRKFKVDASVCLSDIVESCPPRLTGADLYSLCSDAMMCAVKRKISRITEGVDSELSSLTLCSED 1041

  Fly   962 LIESFQTTRPSLSASDVAKYHRTYARFTNK 991
            ..|:....:||:|...:::|.....:.:::
Zfish  1042 FSEALSGLQPSVSEQQISRYQLLQQKLSSR 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729	17/87 (20%)
		CDC48	365..983	CDD:273521	178/650 (27%)
		RecA-like_PEX1_r2	728..885	CDD:410934	87/158 (55%)
pex6	XP_001332652.6	None