Protein Alignment Pex1 and afg2b

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_001070056.2
• Gene: afg2b / 767648
• ZFINID: ZDB-GENE-060929-204
• Length: 748
• Species: Danio rerio
• Alignment Length: 769
• Identity: 190/769 - (24%)
• Similarity: 336/769 - (43%)
• Gaps: 147/769 - (19%)

  Fly   282 CMHTAADK----DYYVRVRTVEDDIEDDLPE------TIHPSIELNANLMKLLGIKELERVVLRP 336
            |:.||..:    |.|:::.:  ..:..||.:      |:||:                   .::|
Zfish    46 CLCTAWPRRDLADGYLQISS--QCVSPDLHKHTLTALTVHPA-------------------QIKP 89

  Fly   337 KTTVVNFVEKIELFANKKTHYKIMENAFKRFVIERTQHKPMLFNQEEVVRLEDDLLVTVGILPEH 401
            .|.:.....|:::|..:..|        |:.|.||:..:.:     :.:.:.:..||.:..:...
Zfish    90 LTCLKLTCVKLKVFVQRLEH--------KKRVSERSLQELL-----DGIYVHEGHLVDLSGVKAE 141

  Fly   402 FRYCVVD--------AQFLKESKIYAADLVRPVGEIIKEETP-PTSPL--------SVQDLIQLP 449
            .|..:|:        |..:..........::.|..:.:::.. ..:||        |::::|..|
Zfish   142 IRCVLVEKVNSGSQRAGLITARTCVDISTIQTVKHLDRQQQQVSAAPLGGMEDVFASLKEMITFP 206

  Fly   450 -EYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFF 513
             .|...:.|        |.||...      .:||.|..|.|||:||..:...:.     ......
Zfish   207 LRYPGSLRQ--------LGLSCPR------GLLLIGPPGVGKTLLVRCVAKDIG-----ATLVTV 252

  Fly   514 HGSRSKGRKTESIQKDLRNIFTSCLQHA---PAIVVLENLDVLA-HAAGEQSSQDGEYYNRMADT 574
            :|....|.:....:::||.:|......|   |.:::::.:|.|. ...|..|:.:    ||:...
Zfish   253 NGPEVTGSRPGESEENLRRVFEQARDAADDGPCVLLIDEIDSLCPRRTGSSSAPE----NRLVAQ 313

  Fly   575 VYQLIVQYTTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILRELCSHIN 639
            :..|:....::....:|...|:..:|:..|..| ||...:.:..:|:|  ..|..||:.:|..:.
Zfish   314 LLTLMDAIGSHEGFVIIGATNQPDSLDPALRRP-GRFDREVIIGVPSL--LQRRSILKCVCREMP 375

  Fly   640 VAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISK---TQPLLTNDQLIESLEHTNSYCLQG 701
            ::.|:||...:.:|.||...||......|...|.|.|:   ::| ::....:::|.|....||:.
Zfish   376 LSPDVDLNTLAEMTCGYVGADLSALSREAALQAMRHSQMGASEP-VSMQHFMQALRHVQPSCLRS 439

  Fly   702 IQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTG 766
                  :....|...:..|::.|||.|...|::.:.||.|:|..|....:....|||||||||..
Zfish   440 ------SIGATDFKPIGWEQIGGLEDVKLKLKQSIEWPMRFPEAFVRLGVSRPRGVLLYGPPGCA 498

  Fly   767 KTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKR-- 829
            ||.||...|:|.:....|:.|.||.:.|:|.||:.:..||.:||:..|.::|.||.||:...|
Zfish   499 KTTLVKAAASSSHCSFFSLSGAELFSPYVGDSEKTLAQLFAQARACAPSIVFLDEVDSMVGSRED 563

  Fly   830 -GHDSTGVTDRVVNQLLTELDGV-----------------EG------------LQ-----GVTV 859
             ...|..|..:|::.||||||||                 ||            ||     .|.:
Zfish   564 GSSSSHSVQSQVLSVLLTELDGVGVRTLERRSTCRKIALLEGGDQEDVRLHQMELQEVCNKDVLI 628

  Fly   860 IAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTANYTG 924
            :|||:|||.||.||||.||:|:::..|.||..||:.:....:.::.|.:.|..:..|.:|..::|
Zfish   629 VAATNRPEALDSALLRPGRLDQIIYVPPPDLQARLAVLRICTKSVPLHQDVCLEDLAAQTELFSG 693

  Fly   925 ADIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQTTRPSLSASDV 978
            ||::::...|.:.|::|       :.||.. .::||:.:::.|...|||||..:
Zfish   694 ADLENLCKEAALLALRE-------DGLAVS-CVRQKYFLKALQMLSPSLSAEQL 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	175/676 (26%)
		RecA-like_PEX1_r2	728..885	CDD:410934	72/193 (37%)
afg2b	NP_001070056.2	CDC48	13..740	CDD:273521	190/769 (25%)