Protein Alignment Pex1 and zgc:136908

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_001035017.1
• Gene: zgc:136908 / 563679
• ZFINID: ZDB-GENE-060312-22
• Length: 805
• Species: Danio rerio
• Alignment Length: 712
• Identity: 198/712 - (27%)
• Similarity: 319/712 - (44%)
• Gaps: 105/712 - (14%)

  Fly   341 VNFVEKIELFANKKTHYKIMENAFKRFVIERTQHKPMLFNQEEVVRLEDDLLVTVGILPEHFR-- 403
            |.:.::|.:.....|...:..|.|..|:      ||........|...|..||..|:....|:
Zfish   110 VKYGKRIHVLPIDDTIEGLTGNLFDVFL------KPYFLEAYRPVHKGDIFLVRGGMRAVEFKVV 168

  Fly   404 ------YCVVDAQFLKESKIYAAD-LVRPVGEIIKEETPPTSPLSVQDLIQLPEYDKI------V 455
                  :|:|           |.| ::...||.||.|....   |:.|:    .||.|      :
Zfish   169 ETDPTPHCIV-----------APDTIIHCEGEPIKREDEEE---SLNDI----GYDDIGGCRKQL 215

  Fly   456 DQVVQELRMNL---CLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSR 517
            .|:.:.:.:.|   .|.....|.....:||.|..|||||::...:.::..     ..|...:|..
Zfish   216 AQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLVARAVANETG-----AFFFLINGPE 275

  Fly   518 SKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQY 582
            ...:.....:.:||..|....::||||:.::.||.:   |.::....||...|:...:..|:...
Zfish   276 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAI---APKREKTHGEVERRIVSQLLTLMDGL 337

  Fly   583 TTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREI------------ILRELC 635
            .....:.|:|..|...:::               |.|....|.||||            ||:...
Zfish   338 KQRAHVVVMAATNRPNSVD---------------AALRRFGRFDREIDIGIPDSTGRLEILQIHT 387

  Fly   636 SHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQ 700
            .::.:::|:||.:.|..|.|:...||......|...|.|...|...|.:|.:...|.::.:..:.
Zfish   388 KNMKLSEDVDLEQISAETHGHVGADLAALCSEAALQAIRKKMTLIDLEDDSIDADLLNSLAVTMD 452

  Fly   701 GIQSNQRTGNDADANEMRV-------EELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGVL 758
            ..:......|.:...|..|       |::.||:.|...|:|::.:|..||..|....:....|||
Zfish   453 DFKWALSQSNPSALRETVVEVPHVNWEDIGGLDEVKRELQELVQYPVEYPDKFLKFGMTPSRGVL 517

  Fly   759 LYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFD 823
            .|||||.|||.|...:|.......:|:||||||..:.|:||.|||::|::||.|.||:|||||.|
Zfish   518 FYGPPGCGKTLLAKAIANECQANFVSIKGPELLTMWFGESEANVRDVFDKARQAAPCILFFDELD 582

  Fly   824 SLAPKRG---HDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVEC 885
            |:|..||   .|:.|..|||:||:|||:||:...:.|.:|.||:||:::|||:||.||:|:|:..
Zfish   583 SIAKARGGGAGDAGGAADRVINQILTEMDGMTNKKNVFIIGATNRPDIIDPAILRPGRLDQLIYI 647

  Fly   886 PLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEAL---AQFG 947
            ||||.|:|..|..|......:.:.||..:.:..|..::|||:..|...|...|::||:   .:..
Zfish   648 PLPDMPSRTAILRANLRKSPVAKDVDLMYLSKITEGFSGADLTEICQRACKLAIREAIEAEIRAE 712

  Fly   948 HEKLAKKIS-----------LKQKHLIESFQTTRPSLSASDVAKYHRTYARFTNKEKTSREF 998
            .::.|:|.:           :::.|..|:.:..|.|:|.:|:.||.    .|....:.||.|
Zfish   713 RQRQARKETAMDDDYDPVPEIRKDHFEEAMRFARRSVSDNDIRKYE----MFAQTLQQSRGF 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	189/671 (28%)
		RecA-like_PEX1_r2	728..885	CDD:410934	76/159 (48%)
zgc:136908	NP_001035017.1	CDC48	27..766	CDD:273521	195/706 (28%)