Protein Alignment Pex1 and drc11

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_073809094.1
• Gene: drc11 / 553364
• ZFINID: ZDB-GENE-050208-768
• Length: 846
• Species: Danio rerio
• Alignment Length: 836
• Identity: 159/836 - (19%)
• Similarity: 262/836 - (31%)
• Gaps: 279/836 - (33%)

  Fly   292 YVRVRTVEDDIEDDLPETIHPSIELNANLMKLLGIKELERVVLRPKTTVVNFVEKIELFANKKTH 356
            |.|:........:||.|..:|::||...       |:..:|.   :|....|:..:::|...:..
Zfish     6 YGRMLDAAQGALEDLLEDEYPTLELRPQ-------KDRLQVF---QTLATFFLRYMKIFRALEEV 60

  Fly   357 YKIMENAFKRFVIERTQHKPM---LFNQEEVVRLE-------DDLLVTVGILPEHF-----RYCV 406
            |..:.:..||.|:.:.....|   :..:.|:|.||       ||||....:.||..     ||.|
Zfish    61 YDQIVHPQKRRVVHQVLDGVMGRLVELKNEMVELEHSEFHYFDDLLQDFKMTPEDLEVPIPRYFV 125

  Fly   407 VD-AQFLKESKIYAADLVRPVGEIIKEETP-------PTSPLSVQDLIQLPEYDKIVDQVVQELR 463
            .: .:.|||.:...|.:      :.||..|       |...:|::..:.|.:..:...|  ..||
Zfish   126 REKMRALKEREKMLAHV------LAKEGRPEHKSVNRPVLSMSMERAVWLLQVSERARQ--GRLR 182

  Fly   464 MNLCLSADNSVMRQCNVLLAGASGTGKTVLVE---RILDQLSRKPDY---CHFEFFHGSRSKGRK 522
            .:..                      ||:.:|   |.|......||.   |..:.:.|.|.:.|.
Zfish   183 AHFM----------------------KTIRLEEQRRHLGSSMLDPDQAATCIQKVWRGYRDRRRV 225

  Fly   523 TESIQKDLRNIFTSCL---QHAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMAD------TV--- 575
            .:...:::  ||...:   |..|:...|....|.......|...:.||...:.:      ||
Zfish   226 NKECLEEM--IFLGMIPAQQQTPSPAQLRAQQVERRRHIIQEEHEAEYQTALVNIKESVRTVDGA 288

  Fly   576 -----------------------------------YQLIVQYTTNNAIAVIATVNELQTLNKRLS 605
                                               ..:..|.|.....|..|...|.:...|:|.
Zfish   289 DIKESLQEQIRQWFLECRDASGKFPDFPSPEDGGSASIFAQKTPEQVAAEFAAKEEEREKKKKLK 353

  Fly   606 S----------------PRG--------------------------------RHVFQTVARLPN- 621
            |                |:|                                :.|:|......|
Zfish   354 SEKDKKANDRKEKKKGKPKGKGGKGDTEEEETGWKMTPSNFLPTVFEGAKLYKEVWQNRDEQQNF 418

  Fly   622 LERADREIILRELCSHINV-------------AKDLDLV-------------------KFSNLTE 654
            |:|.|.:::..|....:.|             .|:|.||                   |......
Zfish   419 LQRFDAQLVREEKRLEVEVELRVQVDELMRQELKNLKLVVDRDKGKKKKKVKKSSKKKKKKGRKT 483

  Fly   655 GYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESL-------------------EHTNSYCLQ 700
            |.:|                 .|.:..||.|:.||||                   ::...|...
Zfish   484 GKKK-----------------KKKEKDLTADRTIESLYEELVLEGIIIRPMNVKLSDYIGEYSYL 531

  Fly   701 GIQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQA---------G 756
            |....|     ||     :|.:|.|..|..::           .::...||.:|.         .
Zfish   532 GTTLRQ-----AD-----IEPMPSLSDVRQLI-----------ALYGILPLGSQCVHERGPLIRA 575

  Fly   757 VLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQS--EENVRNLFNRARSARPCVLFF 819
            :||.||.|.||..||..|.|.....:.::....|..||.|:|  :..:..:|..||..:|.|::.
Zfish   576 LLLTGPQGVGKKMLVHALCTETGANLFNLSPSTLAGKYPGKSGLQLLLHMVFKVARQLQPSVIWI 640

  Fly   820 DE----FDSLAPKRGHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRI- 879
            .:    |....||...:..  ..|:...|...|..::....|.|:..:.||  .|..:....::
Zfish   641 GDAEKTFYKKVPKLEKEME--PKRLKKTLPKILKSIKAEDRVLVVGTSRRP--FDADIKPFCKVY 701

  Fly   880 DRLVECPLPDAPARVRIFEAL--SSTLSLDECVDFDWFAGKTANYT-GADIQSILT 932
            .:::..|.||..:|..:::.|  :....||..:|....|..|..|| |..:|:|.|
Zfish   702 KKIILIPRPDYASRFTLWKELLQAHGALLDPKLDLSSLAKVTDGYTQGHILQAIQT 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	145/763 (19%)
		RecA-like_PEX1_r2	728..885	CDD:410934	36/172 (21%)
drc11	XP_073809094.1	None