Protein Alignment Pex1 and FIGN

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_047300819.1
• Gene: FIGN / 55137
• HGNCID: 13285
• Length: 785
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 84/317 - (26%)
• Similarity: 149/317 - (47%)
• Gaps: 39/317 - (12%)

  Fly   683 TNDQLIESLEHTNSYCLQGIQSNQRT-GNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTIF 746
            :|..:.|.|::|:::.:..:.:...| |...|.|     ::.||:.|..|::|.::||......|
Human   479 SNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWN-----DIAGLDLVKAVIKEEVLWPVLRSDAF 538

  Fly   747 N---ASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNR 808
            :   |.|    ..:||:||.|||||.|...:|:........:.|..|:||::|::|:.:...|..
Human   539 SGLTALP----RSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLV 599

  Fly   809 ARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELDGV--EGLQGVTVIAATSRPELLDP 871
            ||..:|.|:|..:.|.|...:.::......|:..:.|.:||.|  .....:.||.|||:||.:|.
Human   600 ARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDE 664

  Fly   872 ALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECV---DFDWFAGKTANYTGADIQSILTS 933
            : ||...:.||: .||||:.||.:|...|.|  ..:.|:   :|.....:|..::|.|:..:
Human   665 S-LRRYFMKRLL-IPLPDSTARHQIIVQLLS--QHNYCLNDKEFALLVQRTEGFSGLDVAHL--- 722

  Fly   934 ANMAAVKEALAQFGHEKLAKKIS---------LKQKHLIESFQTTRPSLSASDVAKY 981
                 .:||:....|...|..:|         :..:....:|...:||:|..::..|
Human   723 -----CQEAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMY 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	84/317 (26%)
		RecA-like_PEX1_r2	728..885	CDD:410934	50/161 (31%)
FIGN	XP_047300819.1	RecA-like_fidgetin	513..676	CDD:410931	52/168 (31%)
		AAA_lid_3	701..>732	CDD:465537	6/38 (16%)
		Vps4_C	<749..782	CDD:462762	5/26 (19%)