Protein Alignment Pex1 and NSF

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_006169.2
• Gene: NSF / 4905
• HGNCID: 8016
• Length: 744
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 95/251 - (37%)
• Similarity: 137/251 - (54%)
• Gaps: 26/251 - (10%)

  Fly   743 PTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIIS-VKGPELLAKYIGQSEENVRNLF 806
            |.|......::..|:|||||||.|||.|..|:....|.|... |.|||:|.||:|:||.|:|.||
Human   242 PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLF 306

  Fly   807 NRARSARP--------CVLFFDEFDSLAPKRGH--DSTGVTDRVVNQLLTELDGVEGLQGVTVIA 861
            ..|...:.        .::.|||.|::..:||.  .||||.|.||||||:::||||.|..:.||.
Human   307 ADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIG 371

  Fly   862 ATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSS------TLSLDECVDFDWFAGKTA 920
            .|:||:|:|.||||.||::..:|..|||...|::|....::      .||.|  ||....|.:|.
Human   372 MTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSAD--VDIKELAVETK 434

  Fly   921 NYTGADIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQTTRPSLSAS 976
            |::||:::.::.:|...|:..      |.|.:.|:.:..:. .||.|.||....||
Human   435 NFSGAELEGLVRAAQSTAMNR------HIKASTKVEVDMEK-AESLQVTRGDFLAS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	95/251 (38%)
		RecA-like_PEX1_r2	728..885	CDD:410934	67/152 (44%)
NSF	NP_006169.2	CDC48_N	6..83	CDD:215012
		CDC48_2	111..183	CDD:215011
		CDC48	159..>606	CDD:273521	95/251 (38%)
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	67/152 (44%)