Protein Alignment Pex1 and nvl

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_998649.1
• Gene: nvl / 406805
• ZFINID: ZDB-GENE-040426-2871
• Length: 796
• Species: Danio rerio
• Alignment Length: 892
• Identity: 240/892 - (26%)
• Similarity: 367/892 - (41%)
• Gaps: 236/892 - (26%)

  Fly   215 VSNVKNTIQRNKRQDHMERLKKDLRRESSRSFEFRVIRGLWREQAQESDVFVNGKHL-------P 272
            ||.:.:.:|:..|.::..|.:...|.:..:.|..     :..|...|.....| |||       |
Zfish    31 VSAMASELQQQFRIEYGRRNRTAFRIQVEKVFAL-----ICSESDSEFSALEN-KHLAKRARRSP 89

  Fly   273 EFFDLDLFYCMHTAADKDYYVRVRTVEDDIEDDLPETIHPSIELNANLMKLLGIKELERVVLRPK 337
            |..|     ..|..|.          ..|.|||:||..|.: .:|::|..|     .:|..
Zfish    90 EDGD-----GSHVTAS----------STDSEDDIPEHEHTN-HMNSSLTSL-----YQRGA---- 129

  Fly   338 TTVVNFVEKIELFANKKTHYKIMENAFKRFVIERT------------------------------ 372
                         ||..:...|..:....::|::|
Zfish   130 -------------ANASSSSTIQRSLSDDWIIDKTGDRGQESILIDLCEEESSSTTNQRDSSRLE 181

  Fly   373 -QHKPMLFNQEEVVRLEDDLLVTVGILPEHFRYCVVDAQFLKESKIYAADLVRPVGEIIKEETPP 436
             :.|.:...:::..:||:|...:.|: |            .|:||:...:|   ....:|.|...
Zfish   182 KEKKSVKQKRQKKNKLEEDSETSAGV-P------------AKKSKVKGFEL---QFSSVKFEDFG 230

  Fly   437 TSPLSVQDLIQL------PEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVE 495
            .|..:::::.:|      ||       |.|.|          .|:.....||.|..|.|||:|.:
Zfish   231 GSDETLEEVCKLLIHMRHPE-------VYQRL----------GVVPPRGFLLHGPPGCGKTLLAQ 278

  Fly   496 RILDQLS------RKPDYCHFEFFHGSRSKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLA 554
            .:..:.:      ..|:..          .|...||.|| ||.:|...:..||.|:.::.:|.:.
Zfish   279 AVAGETALPLLKISAPELV----------SGVSGESEQK-LRELFEQAISSAPCILFIDEIDAIT 332

  Fly   555 HAAGEQSSQDGEYYNRMADTVYQLIVQYTTNNA------IAVIATVNELQTLNKRLSSPRGRHVF 613
             ...|.:|:|.|  .|:   |.||:......|:      :.||...|...:|:
Zfish   333 -PKRETASKDME--RRI---VAQLLTCMDDLNSMLEPAQVLVIGATNRPDSLD------------ 379

  Fly   614 QTVARLPNLERA---DREI------------ILRELCSHINVAKDLDLVKFSNLTEGYRKCDLVQ 663
                  |.|.||   ||||            ||:.||..|.:..|.|....:.||.||...||:.
Zfish   380 ------PALRRAGRFDREICLGIPDEGARMKILKTLCRKIRLPDDFDFRHLARLTPGYVGADLMA 438

  Fly   664 FVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQRTGND---------ADANEMRV 719
            ....|...|......:| .|.||:..:|  ..:..|..::|:.....|         :|.:...|
Zfish   439 LCREAAMNAVNRILLEP-TTEDQITPTL--ALARLLDLLKSSVSLSEDQLAALCVLMSDFSSSLV 500

  Fly   720 EELP-----GLESV-------VGVLEEV-------LMWPSRYPTIFNASPLRNQAGVLLYGPPGT 765
            ...|     |..:|       ||.|::|       :|.|.:.|..|.|..|...||:||.||||.
Zfish   501 RVQPSAKREGFATVPDVTWADVGALQDVREELHMAIMAPIQNPEQFKALGLSAPAGLLLAGPPGC 565

  Fly   766 GKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRG 830
            |||.|...:|.:..|..|||||||||..|:|:||..||.:|.|.|::.|||:||||.|:|.|:|.
Zfish   566 GKTLLAKAVANASGLNFISVKGPELLNMYVGESERAVRQVFQRGRNSAPCVIFFDEIDALCPRRS 630

  Fly   831 HDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPDAPARVR 895
            ...:|.:.|||||||||:||:|..:.|.::|||:||:::|||:||.||:|:.:...||.|..|..
Zfish   631 EHESGASVRVVNQLLTEMDGMENRRQVFIMAATNRPDIIDPAVLRPGRLDKTLYVGLPPAADRHA 695

  Fly   896 IFEA---------LSSTLSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEAL--AQFGHE 949
            |...         |.|.:||:| :..|   .:...:||||:.:::..|.:.|::..|  || .|.
Zfish   696 ILNTITKGGTKPQLDSDVSLEE-IAHD---ARCETFTGADLSALVREACVNALRVHLDPAQ-THT 755

  Fly   950 KLAKKISLKQKHLIESFQTTRPSLSASDVAKYHRTYARFTNKEKTSR 996
            :.||.|.:.:.|..::|:..|||:|..|...|.|.      :|..||
Zfish   756 ESAKDIRVSRVHFEDAFKKVRPSVSKKDQLMYERL------RETLSR 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	204/720 (28%)
		RecA-like_PEX1_r2	728..885	CDD:410934	81/170 (48%)
nvl	NP_998649.1	Nucleolin_bd	2..71	CDD:465247	8/44 (18%)
		CDC48	<218..796	CDD:273521	195/646 (30%)