Protein Alignment Pex1 and CG14183

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Alignment Length: 1063
• Identity: 192/1063 - (18%)
• Similarity: 357/1063 - (33%)
• Gaps: 349/1063 - (32%)

  Fly    71 KEIGLHENDLVKCALIADVLNLRSVHVTPVSSKDWEIIELSTEKISGSVLEQTRIVNSTQILI-- 133
            |:|...|...|...:.|::..|....|..:|     .|..:|.::....|.:..:.|:||.|:
  Fly    28 KKIEPPEEKAVSYKIYAELYVLYVELVNKLS-----FIYHNTFQVQKRALVRVLVENATQQLMQL 87

  Fly   134 ------------VWINKSMQVALTVDRLKPHMNYGRIDHNTELVV--APN-LYK---GLTNGTSN 180
                        ::|:|    ||...:|.|.          :|||  :|. ||:   .:.|
  Fly    88 KEELKDLEMSEYIYIDK----ALIARKLTPR----------DLVVWRSPQFLYRRPLDIQN---- 134

  Fly   181 GVIEENTKLSRSKTTAQVKDELTEKLTPLTHSSTVSNVKNTIQR------NKRQDHMERLKKDLR 239
             :|.:|......:   :.:::..:...|::.:..:.......:|      |.:.|..:.||...|
  Fly   135 -IIADNRLYMNDE---EKEEKAAQDWVPISEAVKLIQAHERARRARVYKSNIKYDKKKFLKVHQR 195

  Fly   240 RESSRSFEFRVIRGLWREQAQESDVFVNGKHLPEFFDLDLFYCMHTAADK--DYYVRVRTVEDDI 302
            ::.:..|.|:      .:||....|           ...:|......||:  :..::...|.|..
  Fly   196 KKINYKFTFK------PDQAMSIPV-----------KRTIFSADFLKADESCENLIKKDDVADTA 243

  Fly   303 EDDLPETIHPSIELNA--------------NLMK--------LLGIKELERVVLRPKTTVVNFVE 345
            .||  |....:|:.||              .::|        |.|:|:: |.:.||..|..:.
  Fly   244 IDD--EEALSAIQNNAACKIQSCWRGYKTRKIVKIRKRFKEELYGMKKI-RKLKRPNQTANSI-- 303

  Fly   346 KIELFANKKTHYKIMENAFKRFVIERTQHKPMLFNQEEVVRLEDDLLVTVGILPEHFRYCVVDAQ 410
             :|::.|:....|:.|:.......|||:    |........:||        :.:|.|      .
  Fly   304 -MEMYKNEMLKKKLDEDFINLINDERTR----LLQFRSPWMMED--------ISDHIR------A 349

  Fly   411 FLKESKIYAA--------DLVR--PVGEIIKEETPP--------TSPLSVQDLIQLPEYDK---- 453
            :.||  .|.|        |.|:  .|..:|.|...|        ..|||..:|.:|.:.:|
  Fly   350 WFKE--FYDATGNFHPYPDPVKQGTVLVVIDETMTPMEFQESLGKKPLSKAELKKLRDKEKKEKR 412

  Fly   454 IVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRS 518
            ...:.:::|:|       ....|:..:..||....|..:...:.::.:.
  Fly   413 KKKEKLKQLKM-------KEAKRRKKLRDAGVIDIGYELTASKAIENIE---------------- 454

  Fly   519 KGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQYT 583
              ...:...||.||:                               .||.|:..|.:.:.:
  Fly   455 --ETMKKYSKDWRNV-------------------------------DEYLNKNHDPIKEWV---- 482

  Fly   584 TNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILRELCSHINVAKDLD--- 645
                     |..:|..:::.:   ||        .:....|.:.| :|||.     :|||.|
  Fly   483 ---------TEEQLAKIHQEV---RG--------LVDEYMRVEYE-LLREA-----LAKDNDEKY 521

  Fly   646 ---LVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQR 707
               .||:....:..||                  |....:|.|:.:|||.:.    |:.....:.
  Fly   522 KALKVKYPKKKKEKRK------------------KKPKDMTGDRTLESLYNE----LKDAGIIEE 564

  Fly   708 TGN-DAD---------ANEMRVEE-----LPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGV 757
            .|: |.|         |::.|.|:     .|....:..|::|.::....:       .:.....:
  Fly   565 IGHRDFDEFITDFNFVADDTRDEDGLTTLGPAKGDIKMVIQESMLGMGEF-------DVPKPKSL 622

  Fly   758 LLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEF 822
            ||.||..:||..|...:|:..:...::: .||...||....:..:..:...|::.:|.:::.:|.
  Fly   623 LLIGPLNSGKRLLCEIIASELDAVFMNL-SPENTYKYAKDLKYFLHVILKVAKAFQPTIMYIEEA 686

  Fly   823 DSLAPKRGHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRI-------D 880
            ..|..|:                           |...|....|.||..:|  :.:|       |
  Fly   687 HRLFWKK---------------------------VPPEAVEINPRLLGTSL--ASKILKPLKKND 722

  Fly   881 RLVECPLPDAP--ARVRIFEALSSTLSLDECVDFD-----WFAGKTAN-------YTGADIQSIL 931
            ::|.....:.|  |...|..|....|.:.:| |:.     |....|.|       |..:.:..:|
  Fly   723 KIVLVGTSNMPWAANGGIKRAFQKVLLIPKC-DYGTSFLLWLELMTENAPDDMKEYAYSALARVL 786

  Fly   932 TSANMA----AVKEALAQFGHEKLAKKISLKQKHL-----IESF-QTTRPSLSASD---VAKYHR 983
            .:.|..    .|||.|      .:.:|:.||.:.|     :|.| ....|.:...|   :.|:::
  Fly   787 QAYNSGDIDDNVKETL------NIDRKMRLKNEALDPNEFLEYFLSKNEPPIFPPDEKIMDKFNK 845

  Fly   984 TYARFTNKEKTSREFVAKRATLA 1006
            .:......||..:.::|::...|
  Fly   846 WFGSSNKLEKLRKSYMAQKLAKA 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729	18/90 (20%)
		CDC48	365..983	CDD:273521	123/694 (18%)
		RecA-like_PEX1_r2	728..885	CDD:410934	28/163 (17%)
CG14183	NP_649172.3	Adgb_C_mid-like	<201..>278	CDD:412094	17/95 (18%)
		globin helix H	201..232	CDD:412094	8/47 (17%)
		IQCD	247..278	CDD:467745	5/30 (17%)
		IQ motif	259..277	CDD:412094	1/17 (6%)
		P-loop containing Nucleoside Triphosphate Hydrolases	617..750	CDD:476819	31/162 (19%)