Protein Alignment Pex1 and Spast

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_008762708.1
• Gene: Spast / 362700
• RGDID: 1308494
• Length: 614
• Species: Rattus norvegicus
• Alignment Length: 276
• Identity: 83/276 - (30%)
• Similarity: 139/276 - (50%)
• Gaps: 17/276 - (6%)

  Fly   717 MRVEELPGLESVVGVLEEVLMWPSRYPTIFNA--SPLRNQAGVLLYGPPGTGKTYLVSQLATSWN 779
            ::.:::.|.|.....|:|:::.||..|.:|..  :|.|   |:||:||||.|||.|...:|...|
  Rat   337 VKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPAR---GLLLFGPPGNGKTMLAKAVAAESN 398

  Fly   780 LRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQL 844
            ....::....|.:||:|:.|:.||.||..||..:|.::|.||.|||..:|.......:.|:..:.
  Rat   399 ATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEF 463

  Fly   845 LTELDGVE--GLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEAL----SST 903
            |.|.|||:  |...|.|:.||:||:.||.|:||  |..:.|...||:...|:.:.:.|    .|.
  Rat   464 LIEFDGVQSAGDDRVLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEETRLLLLKNLLCKQGSP 526

  Fly   904 LSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEAL-AQFGHEKLAKKISLKQKHLIESFQ 967
            |:..|...   .|..|..|:|:|:.::...|.:..::|.. .|..:...::..:::.....||.:
  Rat   527 LTQKELAQ---LARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLK 588

  Fly   968 TTRPSLSASDVAKYHR 983
            ..:.|:|...:..|.|
  Rat   589 KIKRSVSPQTLEAYIR 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	82/274 (30%)
		RecA-like_PEX1_r2	728..885	CDD:410934	60/160 (38%)
Spast	XP_008762708.1	MIT_spastin	114..193	CDD:239142
		RecA-like_spastin	341..504	CDD:410932	62/167 (37%)
		AAA_lid_3	531..585	CDD:465537	9/56 (16%)
		Vps4_C	<578..610	CDD:462762	6/27 (22%)