Protein Alignment Pex1 and ZK938.3

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_001364588.1
• Gene: ZK938.3 / 191468
• WormBaseID: WBGene00014160
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 732
• Identity: 121/732 - (16%)
• Similarity: 218/732 - (29%)
• Gaps: 283/732 - (38%)

  Fly   311 HPSIELNANLMKLLG--IKELERVVLRPKTTVVNFVEK-------IELFANKKTHYKI------- 359
            |.:.|...:|:.|:.  :|:|.|....|:|.:|:.:..       .|::.|..:.||.
 Worm    33 HQTKERLLHLVTLISSQLKQLNRGENVPRTRMVSNLAGNARKDLIFEIYLNLISFYKTSDRMVSI 97

  Fly   360 --------------------------------MENAFKRFVIERTQHKPMLFNQEEVVRLEDDLL 392
                                            :|:.|..|.|..:      |.||:|.......:
 Worm    98 EGSQTNLKCLLVSAKMLSSFFLDVFTKIPTTHIESGFDEFYISHS------FTQEDVAITSTWRM 156

  Fly   393 VTVGILPEHFRYCVVD----------AQFLKESKIYAADLVRPVGEIIKEETPPTSPLSVQDLIQ 447
            ::...:..|..:..|.          ..|||....:..|...      .|....|..||:
 Worm   157 ISQAAIGHHEHHLEVKRACQEQKAFRESFLKTQTDFDIDFEN------AEAEQETQLLSI----- 210

  Fly   448 LPEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHF-- 510
              ||..:   ::|:|                                ||....:||: :|..|
 Worm   211 --EYAVL---IIQKL--------------------------------ERKYQAISRR-NYVRFVR 237

  Fly   511 ---EFFHG---------------SRSKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAA 557
               ...||               :|::|.....:.:::|....:.|...|...:.:..     |.
 Worm   238 ERAAELHGLKVEIDATQAAIRIQARTRGYFARKLVREMREKELNILNMTPESYIRKRC-----AE 297

  Fly   558 GEQSSQDGEYYNRMADTVYQLIVQYTTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNL 622
            .|:..::|.........:.:.|.::.|:.|.|:           |.|.:    |.|...:.|.::
 Worm   298 RERKRKEGLAGGVGGGEIIEQIEEFNTDLAEAL-----------KLLKT----HFFFPTSDLTDI 347

  Fly   623 ERA-------DREIILRELCSHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQP 680
            :.:       ::|.|.|:.|.. .:...|..::.|.||.....|   :...|...:.:|....|.
 Worm   348 KPSALPIDLNNQETIFRDACFR-GIVSPLAQIELSELTSQREIC---KIENRQFKFDFRSFLVQT 408

  Fly   681 LLTNDQLIESLEHTNSYCLQGIQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTI 745
            :.|.             |..|....|::                       .::.:.|
 Worm   409 VCTP-------------CSLGTWQKQKS-----------------------KDQKMQW------- 430

  Fly   746 FNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNR-- 808
                       :||.|.|.:|||.....::.:.::..:.:             .:||.|:..|
 Worm   431 -----------LLLSGAPDSGKTTWARAISRACHVTHVHI-------------SKNVVNMGKRKI 471

  Fly   809 -------ARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTE--LDGVEGLQGVTVIAATS 864
                   |:..:..::..|..|.:  |:.....|.|.|   |:|..  |..:..::.|.||..|.
 Worm   472 YTVVKKLAKQEKRLLVSIDRIDVM--KKDPKHKGYTHR---QILLRNFLSDLSNIKFVMVIGMTR 531

  Fly   865 RP----------------ELLDPALLRSGRIDRLVEC--------PLPDAPARVRIFEALSSTLS 905
            .|                .|.:|.  .:.|.|..|:|        .||..|.  |||:....|.
 Worm   532 VPLDDLDSYISDLFPLQATLSNPT--NATRYDLAVDCLSRNWEQERLPKFPN--RIFDIEKQTK- 591

  Fly   906 LDECVDFDWFAGKTANY 922
                   |...||.|.:
 Worm   592 -------DQTRGKAAKF 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	105/630 (17%)
		RecA-like_PEX1_r2	728..885	CDD:410934	32/183 (17%)
ZK938.3	NP_001364588.1	IQCD	<253..278	CDD:467745	3/24 (13%)
		AAA	431..545	CDD:459627	26/131 (20%)