Protein Alignment Pex1 and prx-1

DIOPT Version :9

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_510386.2
• Gene: prx-1 / 181538
• WormBaseID: WBGene00004191
• Length: 996
• Species: Caenorhabditis elegans
• Alignment Length: 1030
• Identity: 256/1030 - (24%)
• Similarity: 429/1030 - (41%)
• Gaps: 227/1030 - (22%)

  Fly    61 TEIGINARAAKEIGLHENDLVKCALIADVLNLRSVHVTPVSSKDWEIIELSTEKISGSVLEQTRI 125
            |.:.||:..|:..|.||...|....:........:.|.|.:..|:.:|..|...|....|.|.|:
 Worm    71 TNVFINSVFAEVSGFHEKQEVILEKMESKTYCSHIEVAPRTEDDYSVIAQSQSSIENEFLNQIRL 135

  Fly   126 VNSTQILIVWINKSMQVALTVDRLKPHMNYG-RIDHNTELVVAPNLYKGLTNGTSNGVIEENTKL 189
            |:...|:..:::..:.|...:..:.|..|.. .::::|||.|     :.:|.|:.|
 Worm   136 VSQNMIIPHFLSPGVYVQFRILNIVPASNKPVMLNNDTELHV-----QTVTEGSQN--------- 186

  Fly   190 SRSKTTAQVKDELTEKLTPLTHSSTVSNVKNTIQRNKRQDHMERLKKDLRRE-------SSRSFE 247
                         .||.|      ....|.|.:|....|..:.....:|.:.       ..::.|
 Worm   187 -------------DEKAT------MAQKVSNIVQDLSMQGFLSNYVINLEKTPIIGRVLPKKTVE 232

  Fly   248 FRVIRGLWREQAQESDVFVNGKHLPEFFDLDL----------------FYCMHTAADKDYYVRVR 296
            ..|..||  |:..:|.:::.||....:.:..:                |:.:|.:  .:.|:|
 Worm   233 LWVKSGL--EKLDKSTIYIPGKESCLYSEHGIVEIRSQGRGENEERFQFFYLHRS--PNIYLR-- 291

  Fly   297 TVEDDIEDDLPETIHPSIELNANLMKLLGIKELER--------VVLRPKTTVVNF---------V 344
                          :.|.||:|:|..:....:||.        ..|.|...:..|         :
 Worm   292 --------------NQSNELDASLSHMFESLQLENRCHCVEGTNTLEPYMNIKIFGVTQNRICTL 342

  Fly   345 EKIELFANKKTHYKIME----NAFKRFVIERTQHKPMLFNQE--EVVRLEDDLLVTVGILPEHFR 403
            ...|:...|:|...:.|    |...:.:....|..|:|.:.|  |:....||..:.:.::|. .:
 Worm   343 RYCEIMMEKETFQWVKEFELTNVLTKSLHSELQGNPILLSVEGKELDVAVDDKAIRLKVVPS-MK 406

  Fly   404 YCVVDAQFLKESKIYAADLV-----RPVGEIIKE------------------------ETPPTSP 439
            ..|   :.:.|:..:..||.     :.:|::.::                        :.|.||.
 Worm   407 GLV---KRVTENTCFLFDLTTELIFQQLGDLKQKHGDTENTRRRRKRTEEAEASEQIPQKPETST 468

  Fly   440 L------SVQDLIQLPEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERIL 498
            :      ..:..:|:..:.|::.::.:     :|......||      :.|.:|:|||..::::.
 Worm   469 MENFGFAQNKHFVQIGSHSKLLSELDK-----VCCGGKQHVM------VLGGNGSGKTTFIKKLA 522

  Fly   499 DQLSRKPDYCHFEFFHGSRSKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSSQ 563
            .:||........:....:..|||..:.|:|.|.:.........|:.:.|::.||:.      ...
 Worm   523 RRLSHNSSVTFCKMVPCALLKGRSADIIEKLLSDTLHEMEVKKPSCLFLDDFDVIL------PQI 581

  Fly   564 DGEYYNRMADTVYQLIVQYTTNNAIAVIATVNELQTLNKRLSSP--RGRHVFQTVARLPNLERAD 626
            |.|..:...:.|..:..|......::|:.....|.:||......  |.|.:......|..|.:.|
 Worm   582 DQEQRHLAMEKVVSVFAQKLRTTEVSVVLVAQRLSSLNDGFVEQVMRARPIVSRKIELEQLTKED 646

  Fly   627 REIILRELCSHINVAKDLDLVKFSN-LTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIES 690
            |..|....         |||.:.|: ::|..:|.|           .|..|:.:.|..:
 Worm   647 RCEIFETF---------LDLPENSDIISEIVKKSD-----------GYTFSEIEKLAVS------ 685

  Fly   691 LEHTNSYC-LQGIQSNQRTGNDADANEMRVEE------------------LPGLESVVG------ 730
               .|..| ::|::.         ..|:.||:                  ||.:|.|.|
 Worm   686 ---INVECAIKGVKY---------ITEIEVEKAFECFVAGKMGKIEDGQVLPTMEDVGGMFEQKK 738

  Fly   731 VLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYI 795
            :||:|::||.:||.:|.:..:....|:||:||.|.|||.|.:...::.|..:::|||||||:|||
 Worm   739 LLEQVIIWPRKYPQLFESVGVPVSKGILLHGPSGCGKTLLANATISNSNFSVVNVKGPELLSKYI 803

  Fly   796 GQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELDGVE-GLQGVTV 859
            |.||||||.:|.:|||..||:|||||.||||||||||||||||||||||||||||.| |::||.:
 Worm   804 GASEENVRLVFEKARSCAPCILFFDELDSLAPKRGHDSTGVTDRVVNQLLTELDGAEGGMKGVII 868

  Fly   860 IAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTANYTG 924
            :..|||.:|:|.||||.||.|..|.|..|:...|:.|.:.|::.|...: |||:..|.||..::|
 Worm   869 LGCTSRIDLIDDALLRPGRFDHHVYCGHPEKTERLDIMKVLTNKLKPTD-VDFECLAQKTDGWSG 932

  Fly   925 ADIQSILTSANMAAVKE-ALAQFGHEKLAKKISLKQKHLIESFQTTRPSLSASDV 978
            ||:|.:.|:|.....:: |..:.|.|:  ..:.:.|..:...|..:.|....|.|
 Worm   933 ADLQLLFTNAQFYNARQIAKEEDGLEE--DNVPIDQASIESVFNDSIPKPKRSQV 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:286361	18/75 (24%)
		SpoVK	479..974	CDD:223540	169/524 (32%)
		P-loop_NTPase	480..604	CDD:304359	25/123 (20%)
		AAA	757..887	CDD:278434	84/130 (65%)
prx-1	NP_510386.2	PEX-1N	103..179	CDD:370392	18/80 (23%)
		P-loop_NTPase	481..>522	CDD:393306	10/51 (20%)
		SpoVK	511..938	CDD:223540	160/471 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167107
Domainoid	1	1.000	171	1.000	Domainoid score	I2260
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	280	1.000	Inparanoid score	I1763
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103335
Panther	1	1.100	-	-	LDO	PTHR23077
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R902
SonicParanoid	1	1.000	-	-		X3465
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.920