Protein Alignment Pex1 and cdc-48.1

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_496273.1
• Gene: cdc-48.1 / 174624
• WormBaseID: WBGene00007352
• Length: 809
• Species: Caenorhabditis elegans
• Alignment Length: 867
• Identity: 215/867 - (24%)
• Similarity: 373/867 - (43%)
• Gaps: 150/867 - (17%)

  Fly   185 ENTKLSRSKTTAQVKDELTEKLTPLTHSSTVSNVKNTIQRNKRQDHMERLKKDLRRESSRSFEFR 249
            |..|.:...:||.:||::......:..|....|....:.:.|    |:.|
 Worm    10 EKEKKNDELSTAILKDKVKPNRLIVDQSEQDDNSVIAVSQAK----MDEL--------------- 55

  Fly   250 VIRGLWREQAQESDVFVNGKHLPEFFDLDLFYCMHTAADKDYYVRVRTVEDDIEDDLPETIHPSI 314
               ||:|..|    |.:.||...|                    .|..:..|  :..|   :..:
 Worm    56 ---GLFRGDA----VILKGKKRKE--------------------SVAIIVSD--ESCP---NEKV 88

  Fly   315 ELNANLMKLLGIKELERVVLRPKTTVVNFVEKIELFANKKTHYKIMENAF----KRFVIE--RTQ 373
            .:|..:...|.|:..:.|.:.|... :::..:|.:.....|...:..|.|    |.:.:|  |..
 Worm    89 RMNRVVRNNLRIRLGDVVSITPAPN-LSYGTRIHVLPIDDTIEGLTGNLFDVFLKPYFLEAYRPL 152

  Fly   374 HKPMLFNQEEVVRLEDDLLVTVGILPEHFRYCVVDAQFLKESKIYAADLVRPVGEIIK--EETPP 436
            ||..:|..:..:|..:..:|.....|.    |:|...          .::...|:.||  ||...
 Worm   153 HKGDIFTVQAAMRTVEFKVVETEPAPA----CIVSPD----------TMIHYEGDPIKREEEEES 203

  Fly   437 TSPLSVQDL----IQLPEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERI 497
            .:.:...||    .||.:..::|:..::..::...:    .:.....:||.|..|||||::...:
 Worm   204 MNDIGYDDLGGVRKQLAQIKEMVELPLRHPQLFKAI----GIKPPRGILLFGPPGTGKTLIARAV 264

  Fly   498 LDQLSRKPDYCHFEFFHGSRSKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSS 562
            .::..     ..|...:|.....:.:...:.:||..|..|.::.|||:.::.:|.:   |.::..
 Worm   265 ANETG-----SFFFLINGPEVMSKMSGESESNLRKAFEECEKNQPAILFIDEIDAI---APKREK 321

  Fly   563 QDGEYYNRMADTVYQLIVQYTTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADR 627
            .:||...|:...:..|:......:.:.|||..|...:::               ..|....|.||
 Worm   322 TNGEVERRIVSQLLTLMDGVKGRSNLVVIAATNRPNSID---------------GALRRFGRFDR 371

  Fly   628 EI------------ILRELCSHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQP 680
            ||            |||....::.:|.|:||.:.:|...|:...||......|.....|......
 Worm   372 EIDIGIPDAVGRLEILRIHTKNMKLADDVDLEQIANECHGFVGADLASLCSEAALQQIREKMELI 436

  Fly   681 LLTNDQLIESLEHTNSYCLQGIQSNQRTGNDADANEMRVE-------ELPGLESVVGVLEEVLMW 738
            .|.:||:...:.::.:..::..:..|...:.:...|..||       ::.||::|...|:|::.:
 Worm   437 DLEDDQIDAEVLNSLAVTMENFRFAQGKSSPSALREAVVETPNTTWSDIGGLQNVKRELQELVQY 501

  Fly   739 PSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVR 803
            |..:|..:....::...|||.|||||.|||.|...:|.......||:||||||..:.|:||.|||
 Worm   502 PVEHPEKYLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVR 566

  Fly   804 NLFNRARSARPCVLFFDEFDSLAPKR----GHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATS 864
            ::|::||:|.||||||||.||:|..|    |.|..|.:|||:||:|||:||:...:.|.:|.||:
 Worm   567 DVFDKARAAAPCVLFFDELDSIAKARGGGAGGDGGGASDRVINQVLTEMDGMNAKKNVFIIGATN 631

  Fly   865 RPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTANYTGADIQS 929
            ||:::|||:||.||:|:|:..||||..:|.:|.:|......|.:.:|..:.|..|..::|||:..
 Worm   632 RPDIIDPAVLRPGRLDQLIYIPLPDEASRHQILKASLRKTPLSKDLDLTFLAKNTVGFSGADLTE 696

  Fly   930 ILTSANMAAVKEAL------------AQFGHEKLAKKIS------LKQKHLIESFQTTRPSLSAS 976
            |...|...|::|::            .|...|:|.:..:      :.:.|..|:.:..|.|::.:
 Worm   697 ICQRACKLAIRESIEKEIRIEKERQDRQARGEELMEDDAVDPVPEITRAHFEEAMKFARRSVTDN 761

  Fly   977 DVAKYHRTYARFTNKEKTSREF 998
            |:.||.    .|....:.||.|
 Worm   762 DIRKYE----MFAQTLQQSRGF 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	180/666 (27%)
		RecA-like_PEX1_r2	728..885	CDD:410934	76/160 (48%)
cdc-48.1	NP_496273.1	CDC48	52..775	CDD:273521	203/815 (25%)