Protein Alignment Pex1 and LOC1280986

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_320860.5
• Gene: LOC1280986 / 1280986
• VectorBaseID: AGAMI1_003191
• Length: 736
• Species: Anopheles gambiae
• Alignment Length: 665
• Identity: 184/665 - (27%)
• Similarity: 290/665 - (43%)
• Gaps: 127/665 - (19%)

  Fly   386 RLEDDLLVTVGILPEHFRYCVVD--AQFL------KESKIYAADLVRP-----VGEIIKEETPPT 437
            ||:.|||:|        :.|:.|  |.||      |..:|.....:|.     .|..:||...|
Mosquito   123 RLKVDLLLT--------KECLADTLATFLNRTFFCKGCRIDFTGCLRDRNMGICGVYVKETQGP- 178

  Fly   438 SPLSVQDLIQLPEYDKI--------------VDQVVQELRMNLCLSADNSVMRQCNVLLAGASGT 488
            |.....|...:.:.|:|              :|.|.::|...|..|.        ::||.|.||:
Mosquito   179 SVYGEVDRHTVIKIDQILYHPATLTQKPLGGIDGVREQLEAALTESR--------SLLLIGPSGS 235

  Fly   489 GKTVLVERILDQLSRKPDYCHFEFFHGSRSKGRKTESIQKDLRNIFTSCL-------QHAPAIVV 546
            ||..||:.::.:  |..........|..||...:||:   :||..|....       :..|||::
Mosquito   236 GKYSLVKSVISE--RNLPLFEIRGLHFLRSLPGETEA---ELRQTFLRLRLFQELIEREKPAILL 295

  Fly   547 LENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQY--TTNNAIAVIATVNELQTLNKRLSSPRG 609
            ::::|.:....|.:..:|.....|:|.....|:.||  :..|.| :|.|.:.:::::.||..| |
Mosquito   296 VKDIDTICPKIGAKKGEDVVNIARIASQFVSLVDQYRESAENVI-IIGTTSSVESMDTRLRRP-G 358

  Fly   610 RHVFQTVARLPNLERADREIILRELCSHINVA-----KDLDLVKFSNLTEGYRKCDLVQFVERAI 669
            |...:....:|:.|:  |..|||  |.:....     :.||||  ...|.||...:|    |...
Mosquito   359 RLDKEITLGIPSKEQ--RIDILR--CFYATARGTLTDEQLDLV--GQRTAGYVGAEL----ELLY 413

  Fly   670 FYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQRTGNDADAN-------EMRVEELPGLES 727
            :...|....|.|...:.|.|            ||...|..|..:|.       .:.::...|::.
Mosquito   414 YNLVREMHKQQLPFEEALAE------------IQKKHRPSNLRNATGLVGREATLSLDSFGGMDE 466

  Fly   728 VVGVLE----EVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGP 788
            :..:|.    |.|..|:|:..: ...|||   |:|||||||..||.|...||....:..:|:...
Mosquito   467 LKALLRLCIVEQLANPARFQRL-GIHPLR---GILLYGPPGCAKTTLAKCLAAETGMTFLSLSAA 527

  Fly   789 ELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRG-----HDSTGVTDRVVNQLLTEL 848
            ::.:.|:|.:|:.:..:||.||:..|.|:|.||.|||...||     ..|:.|...|::.||.|:
Mosquito   528 QVYSPYVGDAEKLITRVFNEARTNAPAVVFLDEIDSLVGNRGTGGMKGGSSAVNMGVLSTLLMEM 592

  Fly   849 DGV-----------EGLQGVTVIAATSRPELLDPALLRSGRIDRLVECPLPDAPARVRIFEALSS 902
            ||:           |..:.|.|||||:||:::|.||||.||:.:|:..|.||...|:.|...:::
Mosquito   593 DGIGQAEQAASALSEDAKRVVVIAATNRPDMVDDALLRPGRLTKLIHVPAPDGKGRLEILRKIAT 657

  Fly   903 TLSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQ 967
            .:...|.|..:..|.:|..|:|||:|::.|.|.:.|..|.|         ....:...||..:.|
Mosquito   658 NVPFAEDVQLELVAEQTERYSGADLQNLCTQAALNAATEDL---------NATVVTMAHLRSALQ 713

  Fly   968 TTRPSLSASDVAKYH 982
            ..||||:...:..||
Mosquito   714 DVRPSLTKEQIDWYH 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	184/665 (28%)
		RecA-like_PEX1_r2	728..885	CDD:410934	64/176 (36%)
LOC1280986	XP_320860.5	None