Protein Alignment Pex1 and Pex6

DIOPT Version :10

• Sequence 1: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_063122650.1
• Gene: Pex6 / 117265
• RGDID: 621637
• Length: 1034
• Species: Rattus norvegicus
• Alignment Length: 654
• Identity: 178/654 - (27%)
• Similarity: 286/654 - (43%)
• Gaps: 148/654 - (22%)

  Fly   434 TPPTSPLSVQDLIQLPEYDKIVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERIL 498
            :||...||.      |..:.:|:::...|:.:|...........| |||.|..|:|||..|....
  Rat   427 SPPWDSLSP------PGLEALVNELCAVLKPHLQPGGTLLTGTSC-VLLQGPPGSGKTTAVTAAC 484

  Fly   499 DQLSRKPDYCHFEFFHGSRSKGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAH---AAGEQ 560
            .:|.     .|......|......:.:::..|:..|:...:..|.:::|..||:|..   ..||.
  Rat   485 SRLG-----LHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGLGED 544

  Fly   561 SSQDGEYYNRMADTVYQLIVQ---YTTNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNL 622
            :        |:..|:..|::.   .:....:.|:||.:.:|.|...:     |..|.....:|.|
  Rat   545 A--------RVVATLRHLLLDEDPLSRCPPLMVVATTSRVQDLPTDV-----RTAFPHELEVPVL 596

  Fly   623 ERADREIILRELCSHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQ-------- 679
            ..:.|..:|:.|.:|:.:.::::|.:.:....|:...||...    :.:|.|.:.|:
  Rat   597 SESQRLSVLQALTAHLPLGQEVNLSQLARRCAGFVVGDLYAL----LTHASRAACTRIKAAGLAM 657

  Fly   680 -------------PLLTND--QLIESLEHTNSYCLQGIQSNQRTGNDADANEMRVEELPGLESVV 729
                         |||..|  |.::.|:..:|..:...:....:.:|          :.||:.|.
  Rat   658 SEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHD----------VGGLQDVK 712

  Fly   730 GVLEEVLMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKY 794
            ..:.|.:..|..:|.:.:.. || ::|:||:||||||||.|...:||..:|..:|||||||:..|
  Rat   713 KEILETIQLPLEHPELLSLG-LR-RSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMY 775

  Fly   795 IGQSEENVRNLFNRARSARPCVLFFDEFDSLAPKRGH--DSTGVTDRVVNQLLTELDGVEGLQGV 857
            :||||||||.:|.|||:|.||::||||.|||||.||.  ||.||.||||:|||.||||:...|.|
  Rat   776 VGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDV 840

  Fly   858 TVIAATSRPELLDPALLRSGRIDRLVEC-PLPDAPARVRIFEALSSTLSLD---------ECVDF 912
            .||.||:||:||||||||.||.|:||.. ...|..:::|:..|::....|:         :|.
  Rat   841 FVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLMNVLDCC-- 903

  Fly   913 DWFAGKTANYTGADIQSILTSANMAAVKEALAQF------------------------------- 946
                  ....||||:.|:.:.|.|.|:|..:...
  Rat   904 ------PPQLTGADLYSLCSDAMMTALKRRVRDLEEGEPLPALDGNQETRGDSPGIPEERLSRRH 962

  Fly   947 ---------------------------GHEKLAKKISLKQKHLIESFQTTRPSLSASDVAKYHRT 984
                                       |.|..:..:.|..:.|:::....:||:|..::.:|.|.
  Rat   963 LPRLLSYLGIDYSWGQGSGLTVPRHPSGLEPRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRI 1027

  Fly   985 YARF 988
            ..:|
  Rat  1028 QRKF 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	176/647 (27%)
		RecA-like_PEX1_r2	728..885	CDD:410934	91/158 (58%)
Pex6	XP_063122650.1	None