Protein Alignment MTNR1B and mtnr1bb

DIOPT Version :9

• Sequence 1: NP_005950.1
• Gene: MTNR1B / 4544
• HGNCID: 7464
• Length: 362
• Species: Homo sapiens
• Sequence 2: NP_571469.1
• Gene: mtnr1bb / 30668
• ZFINID: ZDB-GENE-990415-156
• Length: 347
• Species: Danio rerio
• Alignment Length: 354
• Identity: 232/354 - (65%)
• Similarity: 279/354 - (78%)
• Gaps: 13/354 - (3%)

Human     1 MSENGSF-ANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILS 64
            |.||.:| .|..:.|    ..|.:...||||:      |....|::|||.||.|||:||||||:|
Zfish     1 MPENIAFLTNSTDLG----HVGRALGSSARPA------WAIAVLASVLIFTTVVDVLGNLLVIIS 55

Human    65 VLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVF 129
            |.||||||||||:|:||||.||||||||||||:|.|||:|||:|||..||.|.|:||||||||||
Zfish    56 VFRNRKLRNAGNVFVVSLAFADLVVAFYPYPLVLYAIFHDGWSLGETQCKISGFLMGLSVIGSVF 120

Human   130 NITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQ 194
            |||.||||||||||||.||.|:|...:|.|.:.|||.|||:|:|||||||||.||||:|||||.|
Zfish   121 NITGIAINRYCYICHSFAYGRLYSFRNTLLLVALIWALTVLAILPNFFVGSLSYDPRVYSCTFTQ 185

Human   195 TASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVI 259
            |||:.||..|||:|||:|||||:||||||||||:|.|||.|.|.|..::|||||:|:|||||||:
Zfish   186 TASSSYTVVVVVVHFLVPIAVVTFCYLRIWVLVIQVRRKVKSEERSRVRPSDLRNFVTMFVVFVL 250

Human   260 FAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
            |||||||||.|||.|||||:.|||::||.|||.||.:||||||||||:|||||:|||:||.||:.
Zfish   251 FAICWAPLNLIGLVVAINPEVMAPRVPEWLFVVSYFMAYFNSCLNAIIYGLLNRNFRKEYVRIMT 315

Human   325 ALWNPRHCIQDASKGSHAEGLQS-PAPPI 352
            |:|.||..:.:.|:.: .:|::| |:|.|
Zfish   316 AVWIPRRFVTETSRAA-TDGMRSKPSPAI 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTNR1B	NP_005950.1	7tm_4	48..>192	CDD:304433	109/143 (76%)
		7tm_1	57..308	CDD:278431	189/250 (76%)
		7tm_4	<131..>261	CDD:304433	92/129 (71%)
mtnr1bb	NP_571469.1	7tm_4	39..>241	CDD:304433	150/201 (75%)
		7tm_1	48..299	CDD:278431	189/250 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	400	1.000	Domainoid score	I4620
eggNOG	1	0.900	-	-		E33208_3BK64
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4350
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48050
OrthoDB	1	1.010	-	-		D303234at7742
OrthoFinder	1	1.000	-	-		FOG0001264
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_115149
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4597
SonicParanoid	1	1.000	-	-		X2965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	12	12.220