Protein Alignment can and TAF5

DIOPT Version :10

• Sequence 1: NP_524827.1
• Gene: can / 45432
• FlyBaseID: FBgn0011569
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_197897.3
• Gene: TAF5 / 832586
• AraportID: AT5G25150
• Length: 669
• Species: Arabidopsis thaliana
• Alignment Length: 727
• Identity: 173/727 - (23%)
• Similarity: 296/727 - (40%)
• Gaps: 177/727 - (24%)

  Fly   233 DLDEQHNENKCTYWEEMSLRPVDKGEVSQEELMAILNEDES--SPDHRSECDIDEAIRTRDGSDF 295
            ||:..|::|                           |...|  |.|:.::.::.:.||:....:
plant    25 DLESYHHQN---------------------------NNGSSFTSVDYHNDPELTKLIRSFSQQE- 61

  Fly   296 YEDSAQFLENMENVSLLVIKEDSVFADYEFAVKKLIKLIQSTPSHYKYEIYILLYPLLVLTYLQM 360
             :|..::.|                     ...||.....::...||:|:..::||:.:..|:.:
plant    62 -DDPTRYRE---------------------GYSKLRSWAYNSLDLYKHELLRVMYPVFIHCYMDL 104

  Fly   361 MASDKIQKARMLLVRFQDHLDDSYISRIIKLREISKPAEVPNK--ARKLLAGLEKVKIEMSEGAF 423
            :.....|:||.....|:...:..::..:.||..:..|:.:...  ||.|..  .||.|:..:.::
plant   105 VGKGHTQEARAFFNSFRKDHEMVHLRDLQKLEGVLSPSHLEEMEFARSLRK--SKVNIKFCQYSY 167

  Fly   424 RQLLLCTEEWTRGQQEKLL-----SHFQIQPYS-------------------------------- 451
            ..||    ::.......|:     .|...|.||
plant   168 ELLL----QYLHSTVSTLMLGIINEHINFQVYSGQPTSSSDDIEAVTIVGSFQDTANHINQKEIQ 228

  Fly   452 ---------------------------------EDDKPQQRFAIGQPLLEPIWYGAPEPLHKKDF 483
                                             .||..::...||:       .|:.....|||.
plant   229 WGLLEDSLEDRLEKTGGLLSDSEKGQGESKDGDADDSKKRSTEIGK-------QGSSLKKLKKDK 286

  Fly   484 AARPFFQKRRKK----RSEPQLSDNLHLPPVNRVYNPIPNKMDLLHMKSDEQYRMKLDRNNLPST 544
            |.....:..|.:    ...|::...|.||.::     ...:..:|   .|.:.|::|....:||.
plant   287 AGNATAKVARLETITVSPAPRVKPELALPVMS-----TDVEQSIL---EDLRNRVQLSSVAMPSV 343

  Fly   545 YLYTTSPSDEVVICATFSEGNSMLALGTVSSKVYVFSLKPSKLVQVKAAQWLKNLDTGMAGVDKD 609
            ..||...:...:.|::.|...|::|.|...|.:.|:.:  :|:.|.         .:|....:.|
plant   344 SFYTFVNTHNGLNCSSISHDGSLVAGGFSDSSIKVWDM--AKIGQA---------GSGALQAEND 397

  Fly   610 MID----PIKKFTRRTLYGHQGPVYGCSFNPEDRFLITCSEDFSVRLWCLLSWSCVVIFSGHLAP 670
            ..|    |..:.:...|.||.||||..:|:|...|:::.|.|.::|||.....:.:|.:.||..|
plant   398 SSDQSIGPNGRRSYTLLLGHSGPVYSATFSPPGDFVLSSSADTTIRLWSTKLNANLVCYKGHNYP 462

  Fly   671 VCFVVFAPRGYYFATASDDCTARVWMQDNTKPARILQGHLAELGVCLFHPNRHYMATGSADCTVR 735
            |....|:|.|:|||:.|.|.|||:|..|..:|.||:.|||:::....:|||.:|:||||:|.|||
plant   463 VWDAQFSPFGHYFASCSHDRTARIWSMDRIQPLRIMAGHLSDVDCVQWHPNCNYIATGSSDKTVR 527

  Fly   736 IWDIVKAVQVRIFRGHKSRITALIYSICGRYLVSGGDDNLIMIWDTANEILMQFFDHHKASINTM 800
            :||:.....||||.||:|.:.:|..|..|||:.||.:|..||:||.:....:.....|.:.:.::
plant   528 LWDVQTGECVRIFIGHRSMVLSLAMSPDGRYMASGDEDGTIMMWDLSTARCITPLMGHNSCVWSL 592

  Fly   801 EISLDNNILVVGGQDCQLTLWDFEQVIKNYLNRAKISMKNQAGTQESSANNLLVS--SFFTKGEP 863
            ..|.:.::|..|..||.:.|||.....|  |.:|:         :::..:|.|.|  :|.||..|
plant   593 SYSGEGSLLASGSADCTVKLWDVTSSTK--LTKAE---------EKNGNSNRLRSLRTFPTKSTP 646

  Fly   864 FYMIRFTRRNLL 875
            .:.:||:|||||
plant   647 VHALRFSRRNLL 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
can	NP_524827.1	TAF5_NTD2	320..453	CDD:176269	28/204 (14%)
		WD40 repeat	591..624	CDD:293791	5/36 (14%)
		WD40	619..>823	CDD:238121	80/203 (39%)
		WD40 repeat	629..666	CDD:293791	11/36 (31%)
		WD40 repeat	672..708	CDD:293791	16/35 (46%)
		WD40 repeat	713..749	CDD:293791	17/35 (49%)
		WD40 repeat	760..790	CDD:293791	11/29 (38%)
TAF5	NP_197897.3	TFIID_NTD2	61..190	CDD:461330	26/157 (17%)
		WD40 repeat	357..416	CDD:293791	14/69 (20%)
		WD40	<359..662	CDD:441893	110/322 (34%)
		WD40 repeat	422..458	CDD:293791	10/35 (29%)
		WD40 repeat	463..499	CDD:293791	17/35 (49%)
		WD40 repeat	506..541	CDD:293791	17/34 (50%)
		WD40 repeat	547..583	CDD:293791	12/35 (34%)
		WD40 repeat	589..622	CDD:293791	9/34 (26%)