Protein Alignment can and wda

DIOPT Version :10

• Sequence 1: NP_524827.1
• Gene: can / 45432
• FlyBaseID: FBgn0011569
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_651136.1
• Gene: wda / 42750
• FlyBaseID: FBgn0039067
• Length: 743
• Species: Drosophila melanogaster
• Alignment Length: 792
• Identity: 154/792 - (19%)
• Similarity: 285/792 - (35%)
• Gaps: 196/792 - (24%)

  Fly   220 SLSSLDDYDYGETDLDEQHNENKCTYWEEMSLRPVD------------KGEVSQE-----ELMAI 267
            ||.|..::.:..:.:....|.||.:...:.:....|            |..||.|     :.:.:
  Fly     2 SLPSASNHAHAASPVYSNSNNNKSSASSKKTSSKNDLLRCAVGLLLKQKNYVSNERFRRSDFLLL 66

  Fly   268 LNEDESSPDHRSECDIDEAIRTRDGSDFYEDSAQFLENMENVSLLVIKEDSVFADYEFAVKKLIK 332
            .|:.:.:.:...:.|:      ..|:.|...:.|.:.|.::.           .|.:|.  :..:
  Fly    67 QNKQQFAVNKMLDTDL------HGGNSFTFSNVQVITNNQHT-----------VDQQFG--RFSQ 112

  Fly   333 LIQSTPSHYKYEIYILLYPLLVLTYLQMMASDKIQKARMLLVRFQDHLDDSYISRIIKLREISKP 397
            .:::.....:.|:.....|:|...||.::.:.:.:.|..||.::      :::...:.:.:...|
  Fly   113 FVEAQAEPLRLEMKRFYGPMLCHFYLDLLKAREPRGAVELLRKY------AHLVAPVDMYDAPPP 171

  Fly   398 AEV---PNKARKLLAGLEKVKIEMSEG-----AFRQLLLCTEEWTR---GQQEKLLSHFQIQPYS 451
            .::   ...|.:....:...|.....|     .|.:|:.....:||   .:.:..::||:...|.
  Fly   172 TKINGCSTTANESTFNIRFAKEAQDTGDTELDYFMRLVQTLSGYTRLEAAESDDTVAHFRSSKYE 236

  Fly   452 EDDKP----------QQRFAIGQPLLEPIWY---------------------GAPEPLH----KK 481
            .....          |:|   |..|:..:.|                     |..:.|.    :.
  Fly   237 LHTTAVVVNRICAYLQRR---GHVLIMNLLYTWLHVHIVENEQRAFSEDHLLGLTDDLEGEDGED 298

  Fly   482 DFAARP---------------FFQKRRKKRSEPQLSDNLHL-------------PPVNRVYNPIP 518
            |..::|               ..:|..:||  |....|:.|             ..::::...|.
  Fly   299 DVVSKPAVTLNTRGDIRPSKSLTEKSNRKR--PAEEPNIMLETDIKQEVETDESAELSKLQLNID 361

  Fly   519 NKMDLLHMKSDE--QYRMKLDR--------NNLPSTYLYTTSPSDEVVICATFSEGNSMLALGTV 573
            ..:|.|...:::  :.:::|.|        ..|.|.:|   .||:    |       .||| |..
  Fly   362 ACLDTLKSATEQILKSQVELPRFLRISERSRGLTSAHL---DPSE----C-------HMLA-GFD 411

  Fly   574 SSKVYVFSLKPS--------KLVQVKAAQW-LKNLDTGMAGVDKDMIDPIKKFT---RR------ 620
            :|.|.::.|..|        :....|...| |.|........|:|..|...|.:   ||
  Fly   412 NSAVQLWQLNQSYCRGKSFYRRYPQKRCPWELNNCANQEEETDEDSSDEDVKCSEEERRERNRAR 476

  Fly   621 ---------------TLYGHQGPVYGCSFNPEDRFLITCSEDFSVRLWCLLSWSCVVIFSGHLAP 670
                           .|.||...|....|:.....:.:.|:|.::|.|...:..|..|:..|..|
  Fly   477 HCKYADNSYNEYGGFQLRGHTKGVTDVRFSAHYPLMYSVSKDATMRCWRAHNLHCAAIYRSHNYP 541

  Fly   671 VCFVVFAPRGYYFATASDDCTARVWMQDNTKPARILQGHLAELGVCLFHPNRHYMATGSADCTVR 735
            :..:..:|.|.|..|.|.|.:||:|..:......|..||..::....||||.:|:||||||.:||
  Fly   542 IWCLDESPVGQYVVTGSKDLSARLWSLEKEHALIIYAGHTQDVECVAFHPNGNYIATGSADHSVR 606

  Fly   736 IWDIVKAVQVRIFRGHKSRITALIYSICGRYLVSGGDDNLIMIWDTANEILMQFFDHHKASINTM 800
            :|.......:|:|...:..:|.|.:|..|:.|.:.|::..:.|:|.|....:.....|.|||:::
  Fly   607 LWCATSGKLMRVFADCRQAVTQLAFSPDGKMLAAAGEETKVRIFDLAAGAQLAELKDHSASISSL 671

  Fly   801 EISLDNNILVVGGQDCQLTLWDFEQVIKNYLNRAKISMKNQAGTQESSANN----------LLVS 855
            ..|..|..|.....|..|.|||.:::       :.:|..:.||:..|:..|          .||.
  Fly   672 SWSTHNRHLATACSDGTLRLWDIKKL-------SPMSDNSSAGSSSSATTNRVLTVNSSCQRLVD 729

  Fly   856 SFFTKGEPFYMI 867
            .|:...:..|.|
  Fly   730 VFYGTSKTLYCI 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
can	NP_524827.1	TAF5_NTD2	320..453	CDD:176269	21/143 (15%)
		WD40 repeat	591..624	CDD:293791	11/57 (19%)
		WD40	619..>823	CDD:238121	63/224 (28%)
		WD40 repeat	629..666	CDD:293791	8/36 (22%)
		WD40 repeat	672..708	CDD:293791	10/35 (29%)
		WD40 repeat	713..749	CDD:293791	15/35 (43%)
		WD40 repeat	760..790	CDD:293791	7/29 (24%)
wda	NP_651136.1	TAF5_NTD2	104..273	CDD:471824	26/179 (15%)
		WD40	<493..695	CDD:441893	62/201 (31%)
		WD40 repeat	501..537	CDD:293791	7/35 (20%)
		WD40 repeat	542..578	CDD:293791	10/35 (29%)
		WD40 repeat	585..619	CDD:293791	15/33 (45%)
		WD40 repeat	626..662	CDD:293791	9/35 (26%)