DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment can and Wdr38

DIOPT Version :9

Sequence 1:	NP_524827.1	Gene:	can / 45432	FlyBaseID:	FBgn0011569	Length:	942	Species:	Drosophila melanogaster
Sequence 2:	XP_575125.6	Gene:	Wdr38 / 366035	RGDID:	1562587	Length:	299	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	80/271 - (29%)
Similarity:	112/271 - (41%)	Gaps:	37/271 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   556 VICATFSEGNSMLALGTVSSKVYVFSLKPSKLVQVKAAQWLKNLDTGMAGVDKDMIDPIKKFTRR 620
            |.|:.||.....|...:....|||:..|..:|:      |
  Rat    24 VNCSAFSPDGRNLITASDDGCVYVWGTKSGRLL------W------------------------- 57

  Fly   621 TLYGHQGPVYGCSFNPEDRFLITCSEDFSVRLWCLLSWSCVVIFSGHLAPVCFVVFAPRGYYFAT 685
            .|.||:|||..|.|:|:.|.:.:.|.|.::|||.:....|:.:..||...|..|.|:|.....|:
  Rat    58 RLAGHKGPVKSCRFSPDGRLVASSSCDHTIRLWDVAKAKCLHVLKGHQRSVETVSFSPDSKQLAS 122

  Fly   686 ASDDCTARVWMQDNTKPARILQGHLAELGVCLFHPNRHYMATGSADCTVRIWDI---VKAVQVRI 747
            ...|....:|...:.:..|.|.||...:....|.|....:||||.|.||.|||:   ..||..|.
  Rat   123 GGWDKRVILWEVQSGRNVRFLPGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASSPAVSFRN 187

  Fly   748 FRGHKSRITALIYSICGRYLVSGGDDNLIMIW-DTANEILMQFFDHHKASINTMEISLDNNILVV 811
            ..||...|:.|.||..| .|.||..|..:.|| .|.|.:|:| ...|...:|::..|.|...|..
  Rat   188 LEGHTGNISCLKYSASG-LLASGSWDKTVRIWKPTTNNLLLQ-LRGHATWVNSLAFSPDELKLAS 250

  Fly   812 GGQDCQLTLWD 822
            .|....:.:||
  Rat   251 AGYSRMVKVWD 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
can	NP_524827.1	TAF5_NTD2	320..453	CDD:176269
		WD40	<503..829	CDD:225201	80/271 (30%)
		WD40 repeat	591..624	CDD:293791	2/32 (6%)
		WD40	619..>823	CDD:238121	69/208 (33%)
		WD40 repeat	629..666	CDD:293791	11/36 (31%)
		WD40 repeat	672..708	CDD:293791	8/35 (23%)
		WD40 repeat	713..749	CDD:293791	15/38 (39%)
		WD40 repeat	760..790	CDD:293791	13/30 (43%)
Wdr38	XP_575125.6	WD40	<13..298	CDD:225201	80/271 (30%)
		WD40	20..298	CDD:238121	80/271 (30%)
		WD40 repeat	26..61	CDD:293791	11/65 (17%)
		WD40 repeat	67..103	CDD:293791	10/35 (29%)
		WD40 repeat	108..144	CDD:293791	8/35 (23%)
		WD40 repeat	151..189	CDD:293791	15/37 (41%)
		WD40 repeat	195..230	CDD:293791	15/36 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0263
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900