Protein Alignment can and Taf5

DIOPT Version :10

• Sequence 1: NP_524827.1
• Gene: can / 45432
• FlyBaseID: FBgn0011569
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_320836.5
• Gene: Taf5 / 1280962
• VectorBaseID: AGAMI1_007736
• Length: 651
• Species: Anopheles gambiae
• Alignment Length: 650
• Identity: 217/650 - (33%)
• Similarity: 337/650 - (51%)
• Gaps: 86/650 - (13%)

  Fly   284 DEAIRTRDG-SDFYEDSAQFLENMENVSLLVIKEDSVFADYEFAVKKLIKLIQSTPSHYKYEIYI 347
            :|.::...| :|..|:.|.  |...|..|...|.:.....||.:..:|.:.::.:...||:|:.:
Mosquito    24 EELLKKEAGLTDIPENVAG--EAEVNSVLAAYKSEGDPDIYENSYMELRRFVEESLDIYKHELAL 86

  Fly   348 LLYPLLVLTYLQMMASDKIQKARMLLVRFQDHLDDSYISRIIKLREISKPAEVPNK--------- 403
            :|||:||..|::::.:....:|:.|:.:|....:..|...:.||..::|..|:...
Mosquito    87 ILYPVLVHMYIELVYNSHEVQAKKLITKFGPEQEYYYQDELAKLAMVTKRDEMSGNDITDTFKSN 151

  Fly   404 ------ARKLLAGL-----------------EKVKIEMSEGAFRQLLLC-------TEEWTRGQQ 438
                  :|..|:.|                 |.:..::.||..|....|       |.|..| |.
Mosquito   152 AFTIRISRDTLSLLKRHLHEKKASVILNIVNEHMYFDLYEGVARNKAQCDATSGAMTGEAKR-QD 215

  Fly   439 EK------LLSHFQIQ-----PYSEDDKPQQRFAIGQPLLEPIWYGAPEPLHKKDFAARPFFQKR 492
            .|      ||....:|     |..|||.           ::|   .||:...||.....|.|.|
Mosquito   216 NKIKVYYGLLKEPDVQTLVAAPPEEDDD-----------MDP---DAPDKPKKKKPKKDPLFSK- 265

  Fly   493 RKKRSEPQLSDNLHLPPVNRVYNPIP-----NKMDLLHMKSDEQYRMKLDRNNLPSTYLYTTSPS 552
             |.:|:|      :.||::|:  |:|     :||:.:....:...|:.|..:.|||..:||...:
Mosquito   266 -KSKSDP------NAPPLDRI--PLPKLKDVDKMEKIKALRESTKRVNLGPDLLPSICMYTLLNA 321

  Fly   553 DEVVICATFSEGNSMLALGTVSSKVYVFSLKPSKLVQVKAAQWLKNLDTGMAGVDKDMIDPIKKF 617
            :..|.||.|||.:|:|::|.|.|.:.|:|:.|.||.::|:|..||.:|.....|...|:|..|..
Mosquito   322 NHTVTCADFSEDSSLLSVGFVDSSIKVWSMTPMKLREMKSADQLKEIDRDAEDVLIRMLDDRKAE 386

  Fly   618 TRRTLYGHQGPVYGCSFNPEDRFLITCSEDFSVRLWCLLSWSCVVIFSGHLAPVCFVVFAPRGYY 682
            :.|||:||.||||..||.|:...|::||||.:||||.|.:|:|||::.||..||..|.|:|.|:|
Mosquito   387 SCRTLHGHSGPVYRTSFAPDRTMLLSCSEDSTVRLWSLHTWTCVVVYKGHQYPVWDVRFSPHGHY 451

  Fly   683 FATASDDCTARVWMQDNTKPARILQGHLAELGVCLFHPNRHYMATGSADCTVRIWDIVKAVQVRI 747
            |.:.|.|.|||:|..|:.:|.||..|||:::.||:||||.:|:||||:|.|||:||:......|:
Mosquito   452 FVSCSHDRTARLWSTDSHQPLRIFAGHLSDVDVCIFHPNSNYVATGSSDRTVRLWDVCVGNHHRL 516

  Fly   748 FRGHKSRITALIYSICGRYLVSGGDDNLIMIWDTANEILMQFFDHHKASINTMEISLDNNILVVG 812
            ..|||:.|.:|.:|:|||||.||..|..::|||.|:..|:.....|.|||:::..|.|..||..|
Mosquito   517 LTGHKAPIYSLAFSMCGRYLASGSADKRVLIWDLAHGHLIAALTGHTASIHSLCFSRDGTILGTG 581

  Fly   813 GQDCQLTLWDFEQVIKNYLNRAKISMKNQAGTQESSANNLLVSSFFTKGEPFYMIRFTRRNLLLG 877
            |.||.|.||||.:::.: ::...:::.:....::...  .|:.:|.||..||..:.|||||||||
Mosquito   582 GLDCALKLWDFTKLVDD-ISGENVNVSHNPDVRDGEP--YLLRTFPTKQSPFLTLHFTRRNLLLG 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
can	NP_524827.1	TAF5_NTD2	320..453	CDD:176269	37/182 (20%)
		WD40 repeat	591..624	CDD:293791	12/32 (38%)
		WD40	619..>823	CDD:238121	101/203 (50%)
		WD40 repeat	629..666	CDD:293791	19/36 (53%)
		WD40 repeat	672..708	CDD:293791	16/35 (46%)
		WD40 repeat	713..749	CDD:293791	18/35 (51%)
		WD40 repeat	760..790	CDD:293791	14/29 (48%)
Taf5	XP_320836.5	None