Protein Alignment MYO1F and Myo1f

DIOPT Version :9

• Sequence 1: XP_011526326.1
• Gene: MYO1F / 4542
• HGNCID: 7600
• Length: 1119
• Species: Homo sapiens
• Sequence 2: NP_444444.2
• Gene: Myo1f / 17916
• MGIID: 107711
• Length: 1098
• Species: Mus musculus
• Alignment Length: 1125
• Identity: 1006/1125 - (89%)
• Similarity: 1052/1125 - (93%)
• Gaps: 33/1125 - (2%)

Human     1 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPY 65
            |||||||||||||||||||||||||||||||||.:||||||||||||||||||||||||||||||
Mouse     1 MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPY 65

Human    66 FTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKV 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 FTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKV 130

Human   131 SGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195
            ||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 SGGGDKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195

Human   196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGETLSAM 260
            ||||||||||||||||||||||||||:||||||||||||||||||||:|:||||||||.||||||
Mouse   196 RVVMQNENERNFHIYYQLLEGASQEQQQNLGLMTPDYYYYLNQSDTYKVEGTDDRSDFSETLSAM 260

Human   261 QVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRK 325
            ||||||.|:|||||||||||||||||||||:||||||||||||||||||||||||||||||||||
Mouse   261 QVIGIPTSVQQLVLQLVAGILHLGNISFCEEGNYARVESVDLLAFPAYLLGIDSGRLQEKLTSRK 325

Human   326 MDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGF 390
            |||:||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 MDSKWGGRSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQEEYSIGVLDIYGF 390

Human   391 EIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPP 455
            ||||||||||||||||||||||||||||||||||||||||||||||:|||||:||||||||||||
Mouse   391 EIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKLSPP 455

Human   456 GIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERN 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   456 GIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERN 520

Human   521 RDVLFSDLIELMQTSEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCI 585
            |||||||||||||:|:|.||||||||||:.|||||||||||||||||||||:||.:|||||||||
Mouse   521 RDVLFSDLIELMQSSDQDFLRMLFPEKLNIDKKGRPSTAGSKIKKQANDLVSTLKKCTPHYIRCI 585

Human   586 KPNETKRPRDWEENRTGDSPPRGDSAYPPHQSQAPGGIPGPEGEHQGAQSRLRLPPPVRQI---- 646
            |||||||||||||:|.            .||.           |:.|.:..:|    ||:.
Mouse   586 KPNETKRPRDWEESRV------------KHQV-----------EYLGLRENIR----VRRAGFAY 623

Human   647 --PAEPSALRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEV 709
              .......|||||||||||||||||||||||||||||||||||||||||||||||||||||||:
Mouse   624 RRQFSKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEM 688

Human   710 RERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELR 774
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   689 RERKFDGFARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEERPELR 753

Human   775 QFLGKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQA 839
            |||.|||||||||||||||||||||||||||||||||||||||||:|||||.|.||||||:||||
Mouse   754 QFLAKRERVDFADSVTKYDRRFKPIKRDLILTPKCVYVIGREKVKRGPEKGLVREVLKKKLDIQA 818

Human   840 LRGVSLSTRQDDFFILQEDAADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEG 904
            ||||||||||||||||||:||||||||:||||||||||||||||.||||||||||.|||||||||
Mouse   819 LRGVSLSTRQDDFFILQEEAADSFLESIFKTEFVSLLCKRFEEAARRPLPLTFSDLLQFRVKKEG 883

Human   905 WGGGGTRSVTFSRGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPA 969
            ||||.||:||||||..||||||.|||.||:|:|||||||:||||||:|:|:||||:||||||||.
Mouse   884 WGGGSTRNVTFSRGTSDLAVLKAGGRALTISIGDGLPKSTKPTRKGLAQGRPRRSAQAPTRAAPG 948

Human   970 PPRGMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQ 1034
            ||||::|||||||::...|||||.||..:.||||||||::|||||||||||||||:|||||||||
Mouse   949 PPRGLNRNGVPPSSQVRSLPLEITSGRSSQRPPRGPPSSTLGASRRPRARPPSEHSTEFLNVPDQ 1013

Human  1035 GMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGW 1099
            |:||||||||:||||||||||||||||||||||||||||:||||||||||||||||||:||.|||
Mouse  1014 GVAGMQRKRSIGQRPVPGVGRPKPQPRTHGPRCRALYQYIGQDVDELSFNVNEVIEILIEDSSGW 1078

Human  1100 WKGRLHGQEGLFPGNYVEKI 1119
            ||||||||||||||||||||
Mouse  1079 WKGRLHGQEGLFPGNYVEKI 1098

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYO1F	XP_011526326.1	MYSc	12..711	CDD:214580	628/704 (89%)
		MYSc_Myo1	31..698	CDD:276829	597/672 (89%)
		Myosin_TH1	738..918	CDD:283635	168/179 (94%)
		SH3_MyoIe_If_like	1066..1118	CDD:212761	48/51 (94%)
Myo1f	NP_444444.2	MYSc	12..690	CDD:214580	628/704 (89%)
		MYSc_Myo1	31..677	CDD:276829	597/672 (89%)
		Myosin_TH1	717..897	CDD:283635	168/179 (94%)
		SH3_MyoIe_If_like	1045..1097	CDD:212761	48/51 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83965892
Domainoid	1	1.000	1265	1.000	Domainoid score	I988
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56276
Inparanoid	1	1.050	1998	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG55831
OrthoDB	1	1.010	-	-		D122881at2759
OrthoFinder	1	1.000	-	-		FOG0000187
OrthoInspector	1	1.000	-	-		oto112470
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	1	1.100	-	-	LDO	PTHR13140
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2201
SonicParanoid	1	1.000	-	-		X1588
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	16.440