Protein Alignment TrpRS and Wars1

DIOPT Version :10

• Sequence 1: NP_524826.1
• Gene: TrpRS / 45399
• FlyBaseID: FBgn0010803
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_035840.3
• Gene: Wars1 / 22375
• MGIID: 104630
• Length: 481
• Species: Mus musculus
• Alignment Length: 411
• Identity: 257/411 - (62%)
• Similarity: 322/411 - (78%)
• Gaps: 4/411 - (0%)

  Fly    19 GKPDAEPVETGTDAQAQEGATAPTEDVVDPWNVASSNDAGVDYDKLIKRFGSSKIDEELIARFEK 83
            |.|...|. .|.:..:.  ||..:||.||||.|.:|:..|:||||||.:|||||||:|||.|.|:
Mouse    65 GCPPGNPT-AGRNCDSD--ATKASEDFVDPWTVRTSSAKGIDYDKLIVQFGSSKIDKELINRIER 126

  Fly    84 ITGKPAHHFIRRGMFFSHRDLHTILTLREQGKPFYLYTGRGPSSGSLHVGHLVPFIMTKWLQETF 148
            .||:..|.|:|||:||||||::.||...|..|||||||||||||.::|:|||||||.|||||:.|
Mouse   127 ATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVF 191

  Fly   149 DVPLVIQLTDDEKTLWKDLKVEDAIKLGRENAKDIVAIGFDVNKTFIFNNLEFVGKCPAMYQNII 213
            :||||||::||||.|||||.:|.|.....||||||:|.|||:||||||::||::|:.|..|:|::
Mouse   192 NVPLVIQMSDDEKYLWKDLTLEQAYSYTVENAKDIIACGFDINKTFIFSDLEYMGQSPGFYRNVV 256

  Fly   214 RIQKCVTFNQVKGIFGFGDSDIIGKIGFPAAQAAPAISSTFPFIFGNR-KVHCLIPCAIDQDPYF 277
            :|||.||||||||||||.|||.||||.|||.||||:.|::||.||.:| .:.|||||||||||||
Mouse   257 KIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYF 321

  Fly   278 RMTRDVAPRLGFPKCALIHSTFFPALQGAKTKMSASDQNSAVYLTDTPKQIKNKINKYAFSGGRV 342
            |||||||||:|.||.||:|||||||||||:|||||||.||:::||||.||||:|:||:||||||.
Mouse   322 RMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRD 386

  Fly   343 SVEEHRKLGGVPEVDVSYQLLKFFLEDDAKLEEVRVAYSKGEMLTGEIKKLAVETLTPIVEQHQA 407
            :|||||:.||..|||||:..|.||||||.:||::|..|:.|.|||||:||..::.|.|::.:|||
Mouse   387 TVEEHRQFGGNCEVDVSFMYLTFFLEDDDRLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQA 451

  Fly   408 ARKLITDEVLDKYFELRPLKF 428
            .||.:|:|.:.::...|.|.|
Mouse   452 RRKAVTEETVKEFMTPRQLSF 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TrpRS	NP_524826.1	PLN02486	45..426	CDD:178104	247/381 (65%)
Wars1	NP_035840.3	WEPRS_RNA	16..65	CDD:238473	257/411 (63%)
		PLN02486	89..470	CDD:178104	247/380 (65%)
		'HIGH' region	168..177		4/8 (50%)
		'KMSKS' region	353..357		3/3 (100%)