Protein Alignment Aldh-III and aldB

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_418045.4
• Gene: aldB / 948104
• ECOCYCID: EG12292
• Length: 512
• Species: Escherichia coli
• Alignment Length: 478
• Identity: 121/478 - (25%)
• Similarity: 200/478 - (41%)
• Gaps: 49/478 - (10%)

  Fly    57 QLQSESESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRP 121
            ||..|..|....:.|..|..|..........:|..|...|..:....|::...:.:|...|..:|
E. coli    51 QLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLELLATAETWDNGKP 115

  Fly   122 KQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQL 186
            .:|:...:.....:..|:..    ..:::::...|.|:.......:::|.|||..|..||:||.:
E. coli   116 IRETSAADVPLAIDHFRYFA----SCIRAQEGGISEVDSETVAYHFHEPLGVVGQIIPWNFPLLM 176

  Fly   187 LLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELL--NQRFDY 249
            ....:|.|:|||||||:||:.:.......:.:::...|......||.|......|.|  ::|...
E. coli   177 ASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGVVNVVNGAGGVIGEYLATSKRIAK 241

  Fly   250 IFYTGSTRVGKIIHAAANKYLTPTTLELGGKSP------------CYIDKSVDMRTAVKRILWGK 302
            :.:||||.||:.|...|.:.:.|.|||||||||            .:.||:::          |.
E. coli   242 VAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALE----------GF 296

  Fly   303 LI---NCGQTCIAPDYILCSKEVQEKFIVEA-KDVLKEWYGENIQSSPDLSRVINANNFQRLLGL 363
            .:   |.|:.|..|...|..:.:.|:|:..| :.|.....|..:.|...:...::....:.:|..
E. coli   297 ALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESIRSGNPLDSVTQMGAQVSHGQLETILNY 361

  Fly   364 MKSGR-----VAVGGNYDASE------RFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDA 417
            :..|:     |..||.....|      .::|||||.. :....:.:||||||:|.:...::..:|
E. coli   362 IDIGKKEGADVLTGGRRKLLEGELKDGYYLEPTILFG-QNNMRVFQEEIFGPVLAVTTFKTMEEA 425

  Fly   418 IKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGK 482
            ::..|..:..|...|:|.:..|..:..|...:|...:|  ..|.......|||...||:||...|
E. coli   426 LELANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTN--CYHAYPAHAAFGGYKQSGIGRETHK 488

  Fly   483 YGFETFTHKKSCLGKDLS--PLG 503
            ...|.:...| ||....|  |||
E. coli   489 MMLEHYQQTK-CLLVSYSDKPLG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	116/463 (25%)
aldB	NP_418045.4	ALDH_ACDHII_AcoD-like	25..504	CDD:143471	117/470 (25%)