Protein Alignment Aldh-III and betB

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_414846.1
• Gene: betB / 947376
• ECOCYCID: EG10110
• Length: 490
• Species: Escherichia coli
• Alignment Length: 490
• Identity: 116/490 - (23%)
• Similarity: 206/490 - (42%)
• Gaps: 68/490 - (13%)

  Fly    36 ETESPIG---IFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLE 97
            ||.:|..   :.|.|...::.....::|..:..::......::|:|:.             ::..
E. coli    25 ETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIWASMTAMERSRIL-------------RRAV 76

  Fly    98 NLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPK--SFVNM 160
            ::||   |..:|:......|..:...|:..|:.....:.:.:....:.....|:.|.:  ||
E. coli    77 DILR---ERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPALEGSQIPLRETSF--- 135

  Fly   161 MDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-L 224
               |....:|.|||..|||||||:|:.|...|.|:||||.::.||||:....|..:|::..:. |
E. coli   136 ---VYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGL 197

  Fly   225 DNDCYPVVCGGPSETAELLNQR--FDYIFYTGSTRVGKIIHA-AANKYLTPTTLELGGKSPCYID 286
            .:..:.|:.|..:||.:.|.:.  ...:.:||....||.:.| :|...|...|:|||||||..:.
E. coli   198 PDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVF 262

  Fly   287 KSVDMRTAVKRILWGKLINCGQTCIAPDYIL----CSKEVQEKFI-----VEAKDVLKEWYGENI 342
            ...|:..|....:.....:.||.|.....:.    |....::|.:     :.|.||    :....
E. coli   263 DDADLDLAADIAMMANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDV----FDPQT 323

  Fly   343 QSSPDLSRVINANNFQRLL--GLMKSGRVAVGGNYDASERF-----IEPTILVDVKETDPIMEEE 400
            ...| |....:.:|..|.:  |..:..||..||:....:.|     :.||:..|..:...|:.||
E. coli   324 NFGP-LVSFPHRDNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREE 387

  Fly   401 IFGPILPIFNVESAYDAIKFINAREKPLVIYV----FSNSNKLVKEFRRS---TTSGGFSSNETI 458
            ||||::.|...||..:.|:..|..:..|...:    .:.:::::.:....   ..:.|.|..|
E. coli   388 IFGPVMSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE-- 450

  Fly   459 MHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKS 493
                   :|.||...||:||.:|....:::|..||
E. coli   451 -------MPVGGYKHSGIGRENGVMTLQSYTQVKS 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	110/451 (24%)
betB	NP_414846.1	PRK13252	1..490	CDD:183918	116/490 (24%)