Protein Alignment Aldh-III and aldA

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_415933.1
• Gene: aldA / 945672
• ECOCYCID: EG10035
• Length: 479
• Species: Escherichia coli
• Alignment Length: 513
• Identity: 136/513 - (26%)
• Similarity: 220/513 - (42%)
• Gaps: 83/513 - (16%)

  Fly     9 HP-EANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDD 72
            || ..:|..:...||..|..|     .|.||:   :.:..|:.|          :|..|.|  .|
E. coli     7 HPMYIDGQFVTWRGDAWIDVV-----NPATEA---VISRIPDGQ----------AEDARKA--ID 51

  Fly    73 TLQRARLAFSS-GKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKND 136
            ..:||:..:.: ......|:.||....:    .|..:| ||||..:.....|:...||..|..:.
E. coli    52 AAERAQPEWEALPAIERASWLRKISAGI----RERASE-ISALIVEEGGKIQQLAEVEVAFTADY 111

  Fly   137 IRHILFQLDEW--------VQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVAS 193
            |.:    :.||        :||::|.       :::.::....||...|..||:|..|:...:|.
E. coli   112 IDY----MAEWARRYEGEIIQSDRPG-------ENILLFKRALGVTTGILPWNFPFFLIARKMAP 165

  Fly   194 AIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCG-GPSETAELL-NQRFDYIFYTGS 255
            |:..||.:||||||...|.|...|.::.:. |....:.:|.| |.:...||. |.:...:..|||
E. coli   166 ALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGS 230

  Fly   256 TRVGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSK 320
            ...|:.|.|.|.|.:|...||||||:|..:....|:..|||.|:..::||.||.|...:.:...|
E. coli   231 VSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQK 295

  Fly   321 EVQEKFIVEAKDVLKEWYGENIQSSPDLSR--VINANNFQRL-----LGLMKSGRVAVGGN-YDA 377
            .:.::|:....:.::.....|.....|::.  :|||...:|:     ..:.:..|||.||. .:.
E. coli   296 GIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAALERVEQKVARAVEEGARVAFGGKAVEG 360

  Fly   378 SERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFS-NSNKLVK 441
            ...:..||:|:||::...||.||.|||:||:...::..|||...|..:..|...::: |.|..:|
E. coli   361 KGYYYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDAISMANDSDYGLTSSIYTQNLNVAMK 425

  Fly   442 EFRRSTTSGGFSSNETIM-----------HCGVDVLPFGGVGMSGMGRYHGKYGFETF 488
            ..:      |....||.:           |        .|...||:|...||:|...:
E. coli   426 AIK------GLKFGETYINRENFEAMQGFH--------AGWRKSGIGGADGKHGLHEY 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	121/449 (27%)
aldA	NP_415933.1	PRK10090	72..479	CDD:182233	117/428 (27%)