Protein Alignment Aldh-III and ALD5

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_010996.2
• Gene: ALD5 / 856804
• SGDID: S000000875
• Length: 520
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 142/533 - (26%)
• Similarity: 227/533 - (42%)
• Gaps: 102/533 - (19%)

  Fly    15 APINAAGDRPITTVINIEPEPET-ESPIGIFTSQP--ESQQQQPEQLQSESESDRMA-------- 68
            ||:..    |||.     |...| |.|.|:|.:..  .|:|::...:.:.|..:::.
Yeast    26 APLRV----PITL-----PNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMED 81

  Fly    69 NFDDTLQRARLAFSSGKTR----NVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVE 129
            :.|:.:..|:.||   :|:    ....|.|.|.||....|:|: |.::|:|:   ....:||..
Yeast    82 DVDEAVAAAKKAF---ETKWSIVEPEVRAKALFNLADLVEKHQ-ETLAAIES---MDNGKSLFC- 138

  Fly   130 TEFMKNDIRHI---LFQLDEWVQSEKPPKSFVNMMDDVQIY-----NDPFGVVLVIGAWNYPLQL 186
               .:.|:..:   |.....|..     |.:.|::|..:.:     .:|.||...|..||:||.:
Yeast   139 ---ARGDVALVSKYLRSCGGWAD-----KIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLM 195

  Fly   187 LLVPVASAIAAGNCVVIKPSEIAANCAKFIADV-----IPKYLDNDCYPVVCGGPSETAELLNQR 246
            ....:..|:|.||.||:||:|.....|.|.:.:     ||..:.|    ::.|......|.|:..
Yeast   196 WSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVN----ILPGSGRVVGERLSAH 256

  Fly   247 FDY--IFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQT 309
            .|.  |.:||||..|:.|...|...:...|||||||||..:....|:..|||.|.:|...|.|:.
Yeast   257 PDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEV 321

  Fly   310 CIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQ---------------SSPDLSRVINANNFQR 359
            |.|...|.....|.|:.:.:.||     |.|:::               |...|.::::..:..:
Yeast   322 CCAGSRIYIQDTVYEEVLQKLKD-----YTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAK 381

  Fly   360 LLGLMKSGRVAVGG-NYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINA 423
            ..|    .|:..|| .:.:...|::||:..||||...|::||:||||:.:....:..:.|...|.
Yeast   382 SEG----ARLVTGGARHGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMAND 442

  Fly   424 REKPLVIYVFSNS-NKLV---KEFRRST----TSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYH 480
            .:..|...:.:|. ||.|   |..:..|    |...|..|          :||||.|.||:||..
Yeast   443 SQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQN----------VPFGGFGQSGIGREM 497

  Fly   481 GKYGFETFTHKKS 493
            |:.....:|..||
Yeast   498 GEAALSNYTQTKS 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	127/465 (27%)
ALD5	NP_010996.2	ALDH_F1-2_Ald2-like	41..513	CDD:143410	135/509 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810