Protein Alignment Aldh-III and MSC7

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_011904.1
• Gene: MSC7 / 856434
• SGDID: S000001081
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 545
• Identity: 149/545 - (27%)
• Similarity: 234/545 - (42%)
• Gaps: 101/545 - (18%)

  Fly     8 PHPEANGAPINAAGDRPITTVINI----EPE------PETESPIGIFTSQPESQQQQPEQLQSES 62
            |.|||  |..|..|.|.::|  ||    ||.      |.|...:|.|.|:.|
Yeast    84 PAPEA--AQNNWKGKRSVST--NIWNPEEPNFIQCHCPATGQYLGSFPSKTE------------- 131

  Fly    63 ESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEII----------SALEAD 117
                 |:.|:.:.:|..|.|:....:.|.|.:.|.: |..|..:..::|          :.|:|.
Yeast   132 -----ADIDEMVSKAGKAQSTWGNSDFSRRLRVLAS-LHDYILNNQDLIARVACRDSGKTMLDAS 190

  Fly   118 LRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKS--FVNMMDDVQIYNDPFGVVLVIGAW 180
            :     ..::|..|.::..|:|....|.   .|.:|..:  |:......:|..:|.||:..|.:|
Yeast   191 M-----GEILVTLEKIQWTIKHGQRALQ---PSRRPGPTNFFMKWYKGAEIRYEPLGVISSIVSW 247

  Fly   181 NYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKYL---DND------CYPVVCGGP 236
            |||...||.|:.:|:..||.:|:|.||.....::|..::|.|.|   |.|      ||   |..|
Yeast   248 NYPFHNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLEACDEDPDLVQLCY---CLPP 309

  Fly   237 SETAELLN-----QRFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYI---DKSVDMRT 293
            :|..:..|     ..|.:|.:.||..|...|...|.|.|||..:|||||....:   .|::|..:
Yeast   310 TENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTPVVVELGGKDAFIVLDSAKNLDALS 374

  Fly   294 AVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKD-----VLKEWYGENIQ--SSPDLSRV 351
            ::  |:.|...:.||.||..:.::.|||..:..:....|     .|::  |.:|.  .:.|:..:
Yeast   375 SI--IMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTANPLRQ--GSDIDHLENVDMGAM 435

  Fly   352 INANNFQRLLGLM-----KSGRVAVGGN------YDASERFIEPTILVDVKETDPIMEEEIFGPI 405
            |:.|.|..|..|:     |..|:..||:      |.....| :||:||||.....|.:.|:||||
Yeast   436 ISDNRFDELEALVKDAVAKGARLLQGGSRFKHPKYPQGHYF-QPTLLVDVTPEMKIAQNEVFGPI 499

  Fly   406 LPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNE--TIMHCGVDVLPF 468
            |.:...::....::..|:....|...||....|.......|..:|..:.|:  |...|   .|||
Yeast   500 LVMMKAKNTDHCVQLANSAPFGLGGSVFGADIKECNYVANSLQTGNVAINDFATFYVC---QLPF 561

  Fly   469 GGVGMSGMGRYHGKYGFETFTHKKS 493
            ||:..||.|::.|:.|.....:.||
Yeast   562 GGINGSGYGKFGGEEGLLGLCNAKS 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	128/471 (27%)
MSC7	NP_011904.1	ALDH_F15-22	115..590	CDD:143416	136/510 (27%)