Protein Alignment Aldh-III and ALD2

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_013893.1
• Gene: ALD2 / 855206
• SGDID: S000004780
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 150/513 - (29%)
• Similarity: 232/513 - (45%)
• Gaps: 90/513 - (17%)

  Fly    38 ESPIGIFTSQ---PESQQQQPE-----------QLQSESESDRMANFDDTLQRARLAFSSGKTRN 88
            :.|:|:|.:.   |.|..:..|           ..|:.:|.|    .|..::.||.||.:..::.
Yeast    18 KQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKD----VDKAVKAARAAFDNVWSKT 78

  Fly    89 VSFRRK-QLENLLRCYEEHENEIISALEA-DLRRPKQESLIVETEFMKNDIRHILFQL------- 144
            .|.:|. .|.|||:..|| |.:.::|||. |..:|...:       .|.|:..|| ||
Yeast    79 SSEQRGIYLSNLLKLIEE-EQDTLAALETLDAGKPYHSN-------AKGDLAQIL-QLTRYFAGS 134

  Fly   145 -DEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEI 208
             |::.:....|.:|......:::   |||||..|..|||||.:....:..|:||||.|:|||:|.
Yeast   135 ADKFDKGATIPLTFNKFAYTLKV---PFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAEN 196

  Fly   209 AANCAKFIADVIPKYLDNDCYP-----VVCGGPSETAELL--NQRFDYIFYTGSTRVGK-IIHAA 265
            .:....:.|.:|.|    ..:|     :|.|..|...:.|  :...|.|.:||||:||. ::.|:
Yeast   197 TSLSLLYFATLIKK----AGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEAS 257

  Fly   266 ANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEA 330
            ....|...|||.|||||..:.:..|:..|:..|..|...|.||.|.|...:.....:.:||:.:.
Yeast   258 GQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKF 322

  Fly   331 KDVL-KEW--------YGENIQSSPDLSRVINANNFQRL------------LGLMKSGRVAVGGN 374
            |:.. |||        :.|.....|    ||::..:.|:            |.:.::....:||
Yeast   323 KETAKKEWDVAGKFDPFDEKCIVGP----VISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGG- 382

  Fly   375 YDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKL 439
              |...||.|||..||.:|..::::|||||::.:....:..||:|..|.....|...||:...|.
Yeast   383 --AKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKK 445

  Fly   440 VKEFRRSTTSGGF---SSNETIMHCGVDV-LPFGGVGMSGMGRYHGKYGFETFTHKKS 493
            ...|.|...:|..   |||:.      || :||||..|||:||..|:.|.:|:...|:
Yeast   446 AHMFARDIKAGTVWINSSNDE------DVTVPFGGFKMSGIGRELGQSGVDTYLQTKA 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	140/465 (30%)
ALD2	NP_013893.1	ALDH_ALD2-YMR170C	14..502	CDD:143462	150/513 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1337
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760