Protein Alignment Aldh-III and ALD3

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_013892.1
• Gene: ALD3 / 855205
• SGDID: S000004779
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 514
• Identity: 150/514 - (29%)
• Similarity: 232/514 - (45%)
• Gaps: 79/514 - (15%)

  Fly    38 ESPIGIFTSQ---PESQQQQPE-----------QLQSESESDRMANFDDTLQRARLAFSSGKTRN 88
            :.|:|:|.:.   |.|..:..|           ..|:.:|.|    .|..::.||.||.:..::.
Yeast    18 KQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKD----VDKAVKAARAAFDNVWSKT 78

  Fly    89 VSFRRK-QLENLLRCYEEHENEIISALEA-DLRRP-----KQE-SLIVETEFMKNDIRHILFQLD 145
            .|.:|. .|.|||:..|| |.:.::|||. |..:|     ||: :.|:|.      .|:....:|
Yeast    79 SSEQRGIYLSNLLKLIEE-EQDTLAALETLDAGKPFHSNAKQDLAQIIEL------TRYYAGAVD 136

  Fly   146 EWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAA 210
            ::...|..|.:|......:::   |||||..|..|||||.:....:..|:||||.|:|||:|..:
Yeast   137 KFNMGETIPLTFNKFAYTLKV---PFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTS 198

  Fly   211 NCAKFIADVIPKYLDNDCYP-----VVCGGPSETAELLNQRFDY--IFYTGSTRV-GKIIHAAAN 267
            ....:.|.:|.|    ..:|     |:.|..|...:.|....|.  |.:||||:| |.::.|:..
Yeast   199 LSLLYFATLIKK----AGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQ 259

  Fly   268 KYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKD 332
            ..|...|||.|||||..:.:..|:..|::.:..|...|.||.|.|...:.....:.:||:.:.|:
Yeast   260 SNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKE 324

  Fly   333 VL-KEW--------YGENIQSSPDLSRVINANNFQRL------------LGLMKSGRVAVGGNYD 376
            .. |||        :.|.....|    ||::..:.|:            |.:.::....:||
Yeast   325 TAKKEWDVAGKFDPFDEKCIVGP----VISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGG--- 382

  Fly   377 ASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVK 441
            |...||.|||..||.||..::.:|||||::.:....:..||:|..|.....|...||:...|...
Yeast   383 AKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAH 447

  Fly   442 EFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLS 500
            .|.|...:|....|:|...  ...:||||..|||:||..|..|.:.:...|| :..|||
Yeast   448 MFARDIKAGTVWINQTNQE--EAKVPFGGFKMSGIGRESGDTGVDNYLQIKS-VHVDLS 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	140/466 (30%)
ALD3	NP_013892.1	ALDH-SF	14..502	CDD:448367	147/511 (29%)