DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aldh-III and ALDH3H1

DIOPT Version :9

Sequence 1:	NP_724562.2	Gene:	Aldh-III / 45398	FlyBaseID:	FBgn0010548	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_175081.1	Gene:	ALDH3H1 / 841020	AraportID:	AT1G44170	Length:	484	Species:	Arabidopsis thaliana

Alignment Length:	467	Identity:	202/467 - (43%)
Similarity:	286/467 - (61%)	Gaps:	15/467 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEF 132
            |...:.:...|.:|..|.||...:|..||:.|:...:.||.||::||..||.:|:.||.:.|...
plant    10 AEASNLVTELRRSFDDGVTRGYEWRVTQLKKLMIICDNHEPEIVAALRDDLGKPELESSVYEVSL 74

  Fly   133 MKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAA 197
            ::|.|:..|.||..|:..||...|........:|.::|.||||||.|||||..|.:.||..||:|
plant    75 LRNSIKLALKQLKNWMAPEKAKTSLTTFPASAEIVSEPLGVVLVISAWNYPFLLSIDPVIGAISA 139

  Fly   198 GNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELLNQRFDYIFYTGSTRVGKII 262
            ||.||:||||:|...:..:..::.:|||.....||.|..:||:.||.|::|.||||||:::|::|
plant   140 GNAVVLKPSELAPASSALLTKLLEQYLDPSAVRVVEGAVTETSALLEQKWDKIFYTGSSKIGRVI 204

  Fly   263 HAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKL-INCGQTCIAPDYILCSKEVQEKF 326
            .|||.|:|||..||||||||..:|...|::..|:||:.||. .|.||.|::|||||.:||...|.
plant   205 MAAAAKHLTPVVLELGGKSPVVVDSDTDLKVTVRRIIVGKWGCNNGQACVSPDYILTTKEYAPKL 269

  Fly   327 IVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMK----SGRVAVGGNYDASERFIEPTIL 387
            |...|..|:::||:|...|.|:||::|:|:|.||..|:.    |.::..||..|.....|.||||
plant   270 IDAMKLELEKFYGKNPIESKDMSRIVNSNHFDRLSKLLDEKEVSDKIVYGGEKDRENLKIAPTIL 334

  Fly   388 VDVKETDPIMEEEIFGPILPIF---NVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTS 449
            :||.....||.||||||:|||.   |:|.::|.|:   :|.|||..|:|:::.||.:.|..:.::
plant   335 LDVPLDSLIMSEEIFGPLLPILTLNNLEESFDVIR---SRPKPLAAYLFTHNKKLKERFAATVSA 396

  Fly   450 GGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPY 514
            ||...|:..:|..:..|||||||.||||.||||:.|:.|:|||:.|.:.|  .|:  |:.|||||
plant   397 GGIVVNDIAVHLALHTLPFGGVGESGMGAYHGKFSFDAFSHKKAVLYRSL--FGD--SAVRYPPY 457

  Fly   515 SDRKGSLLSFLL 526
            |..|..||..|:
plant   458 SRGKLRLLKALV 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	195/450 (43%)
ALDH3H1	NP_175081.1	PLN02174	1..484	CDD:177831	202/467 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	348	1.000	Domainoid score	I227
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I564
OMA	1	1.010	-	-		QHG62894
OrthoDB	1	1.010	-	-		D646662at2759
OrthoFinder	1	1.000	-	-		FOG0000656
OrthoInspector	1	1.000	-	-		otm2784
orthoMCL	1	0.900	-	-		OOG6_100557
Panther	1	1.100	-	-	LDO	PTHR43570
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X395
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840