Protein Alignment Aldh-III and Aldh1b1

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_082546.1
• Gene: Aldh1b1 / 72535
• MGIID: 1919785
• Length: 519
• Species: Mus musculus
• Alignment Length: 519
• Identity: 147/519 - (28%)
• Similarity: 221/519 - (42%)
• Gaps: 74/519 - (14%)

  Fly     8 PHPEA--NGAPIN-----AAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESD 65
            |:||.  |...||     |...:...||     .|.|...||                 ..:|.|
Mouse    32 PNPEICYNKLFINNEWHDAVSKKTFPTV-----NPTTGEVIG-----------------HVAEGD 74

  Fly    66 RMANFDDTLQRARLAFSSGK--TRNVSFRRKQLENLLRCYEEHENEIISALEA-DLRRPKQESLI 127
            | |:.|..::.||.||..|.  .|..:..|.:|.|.|....|.:...:::||. |..:|.|||.:
Mouse    75 R-ADVDLAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYV 138

  Fly   128 VETEFMKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQI---YNDPFGVVLVIGAWNYPLQLLLV 189
            ::.:.:....|:.....|:|.....|       ||....   .::|.||...|..||:||.:...
Mouse   139 LDLDEVIKVYRYFAGWADKWHGKTIP-------MDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGW 196

  Fly   190 PVASAIAAGNCVVIKPSEIAANCAKFIADVI-----PKYLDNDCYPVVCG-GPSETAELL-NQRF 247
            .:|.|:|.||.||:|.:|.....|.::|.:|     |..:.|    ::.| ||:..|.:. :...
Mouse   197 KLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVN----IITGYGPTAGAAIAQHMDV 257

  Fly   248 DYIFYTGSTRVGKIIH-AAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCI 311
            |.:.:||||.||.:|. ||....|...|||||||||..:....||..||.:.......|.||.|.
Mouse   258 DKVAFTGSTEVGHLIQKAAGESNLKRVTLELGGKSPSIVLADADMEHAVDQCHEALFFNMGQCCC 322

  Fly   312 APDYILCSKEVQEKFIVEAKDVLKEW-----YGENIQSSPDLSRVINANNFQRLLGLM----KSG 367
            |.......:.:..:|:....:..|:.     :..:.|..|.    ::...|:|:||.:    |.|
Mouse   323 AGSRTFVEESIYREFLERTVEKAKQRKVGNPFELDTQQGPQ----VDKEQFERILGYIRLGQKEG 383

  Fly   368 RVAVGGNYDASER--FIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVI 430
            ...:.|.....||  ||:||:..||::...|.:||||||:.|:|..:...:.|:..|.....|..
Mouse   384 AKLLCGGERLGERGFFIKPTVFGDVQDGMRIAKEEIFGPVQPLFKFKKIEEVIQRANNTRYGLAA 448

  Fly   431 YVFSNSNKLVKEFRRSTTSGGFSSNE-TIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKS 493
            .||:........|.::..:|....|. .|:.|..   ||||...||.||..|:.|...:|..|:
Mouse   449 AVFTRDLDKAIYFTQALQAGTVWVNTYNIVTCHT---PFGGFKESGNGRELGEDGLRAYTEVKT 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	129/448 (29%)
Aldh1b1	NP_082546.1	PLN02466	22..518	CDD:215259	147/519 (28%)
		ALDH_F1AB_F2_RALDH1	33..513	CDD:143459	146/518 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810