Protein Alignment Aldh-III and Aldh3b3

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001419525.1
• Gene: Aldh3b3 / 688778
• RGDID: 1585230
• Length: 479
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 227/479 - (47%)
• Similarity: 330/479 - (68%)
• Gaps: 12/479 - (2%)

  Fly    49 ESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISA 113
            :.:..||:|....        |::.|||.:.||::|||:...||.:|||:|.:..:::..::..|
  Rat     4 KGKHPQPDQGTDP--------FEEKLQRLKEAFNTGKTKMAKFRAEQLESLGQFLQDNSKQLHDA 60

  Fly   114 LEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIG 178
            |:.||.:...||.:.|....:|::...|..|..|::.|....:|:.......|..:|||:||:|.
  Rat    61 LDGDLGKSAFESDMSEIILCQNEVDLALKNLQTWMKDESVSTNFLTKFSSAFIRKEPFGLVLIIA 125

  Fly   179 AWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELL 243
            .|||||.|:::|:..|||||||||:||||::.|..|.:|:::|:|||..|:.||.|||.||.:||
  Rat   126 PWNYPLNLMIMPLVGAIAAGNCVVLKPSEMSKNTEKVLAELLPQYLDQSCFAVVLGGPEETGQLL 190

  Fly   244 NQRFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQ 308
            ..:|||||:|||.|||||:.|||.|:|||.|||||||:|||:|.:.|.:|...|:.|.:..|.||
  Rat   191 KHKFDYIFFTGSPRVGKIVMAAAAKHLTPITLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQ 255

  Fly   309 TCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSGRVAVGG 373
            ||:||||:|||:|:||:.:...::.:..:||:|.|:||:|.|:||..:|:||.||:..||||:||
  Rat   256 TCVAPDYVLCSQEMQERLVPALQNAITRFYGDNPQTSPNLGRIINQKHFERLQGLLGCGRVAIGG 320

  Fly   374 NYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNK 438
            ..|..||:|.||:||||:||:|:|:|||||||||:..|.:..:||:|||.|||||.:|.:||:.:
  Rat   321 QSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRNLDEAIEFINRREKPLALYAYSNNVE 385

  Fly   439 LVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLG 503
            ::|:....|:||.|..|:..||..:..|||||||.|||||||||:.|:||:::::||   ||..|
  Rat   386 VIKQVLARTSSGSFCGNDGFMHMTLSSLPFGGVGSSGMGRYHGKFSFDTFSNQRACL---LSCSG 447

  Fly   504 -EKLSSARYPPYSDRKGSLLSFLL 526
             |||:..||||||.|:..||.:.:
  Rat   448 MEKLNDLRYPPYSPRRQQLLRWAM 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	218/443 (49%)
Aldh3b3	NP_001419525.1	ALDH_F3AB	18..460	CDD:143450	218/444 (49%)