Protein Alignment Aldh-III and Aldh3a2

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_006246591.1
• Gene: Aldh3a2 / 65183
• RGDID: 61866
• Length: 584
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 241/525 - (45%)
• Similarity: 337/525 - (64%)
• Gaps: 25/525 - (4%)

  Fly    40 PIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYE 104
            |...|:|.|..::|                    :||.|..|.||::|.:.||.:|||.|.|..:
  Rat    68 PRSAFSSGPAMERQ--------------------VQRLRQTFRSGRSRPLRFRLQQLEALRRMVQ 112

  Fly   105 EHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQIYND 169
            |.|.:|::|:.|||.:.:..:...|...:..:|..:|..|.|...:....|:.:.|||:..:..:
  Rat   113 EREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKNLLTMMDEAYVQPE 177

  Fly   170 PFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCG 234
            |.||||:|||||||..|.|.|:..||||||..::||||::.|.||.:|:::|:|||.|.|.:|.|
  Rat   178 PLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQYLDQDLYMIVNG 242

  Fly   235 GPSETAELLNQRFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRIL 299
            |..||.|||.||||:|.|||:|.||||:..||.|:|||.|||||||||||||:..|:..|.:||.
  Rat   243 GVEETTELLRQRFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRIT 307

  Fly   300 WGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLM 364
            |||.:||||||||||||||...:|::.:.:.||.:|::||||:::|||..|:||..:|:|:..|:
  Rat   308 WGKYMNCGQTCIAPDYILCEASLQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKSLL 372

  Fly   365 KSGRVAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLV 429
            :..::|.||..|.:.|:|.||||.||.....:|:||||||||||.:|::..:||.|||.|||||.
  Rat   373 EGQKIAFGGETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAINFINDREKPLA 437

  Fly   430 IYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSC 494
            :|:||::|||:|.....|:|||.:.|:.|||..|:.|||||||.||||.|||||.|:||:|::.|
  Rat   438 LYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPC 502

  Fly   495 LGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRPLPNLHLSHVLAIGLGVGLTVLTNYYL-- 557
            |.|.|.  ||.::..||||.|:.|.|...|.|.|:.....|.|..::.: :.|...::..|..
  Rat   503 LLKGLK--GESVNKLRYPPNSESKVSWSKFFLLKQFNKGRLQLLLLVCL-VAVAAVIVKKYQALW 564

  Fly   558 QGKLL 562
            :||.|
  Rat   565 RGKAL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	223/442 (50%)
Aldh3a2	XP_006246591.1	ALDH_F3AB	82..521	CDD:143450	223/440 (51%)