Protein Alignment Aldh-III and ALDH8A1

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_072090.1
• Gene: ALDH8A1 / 64577
• HGNCID: 15471
• Length: 487
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 113/454 - (24%)
• Similarity: 188/454 - (41%)
• Gaps: 80/454 - (17%)

  Fly   104 EEHENEIISALEA----DLRRPKQESLIVETEFMKNDIRHILFQ-LDEWVQSEKP---------- 153
            :|.|..:.:|.||    ..|.|::.|.::      |.:..:|.| |:|:.|:|..
Human    45 DEIEAAVKAAREAFPSWSSRSPQERSRVL------NQVADLLEQSLEEFAQAESKDQGKTLALAR 103

  Fly   154 ----PKSFVN----------------MMDDV----QIYNDPFGVVLVIGAWNYPLQLLLVPVASA 194
                |:|..|                .||.:    .....|.||..:|..||.||.||...:|.|
Human   104 TMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPA 168

  Fly   195 IAAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYP-----VVCGGPSETAELL--NQRFDYIFY 252
            :||||.|:.||||:.:..|..:.    |.||....|     :|.|......|.|  :.....|.:
Human   169 MAAGNTVIAKPSELTSVTAWMLC----KLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISF 229

  Fly   253 TGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYIL 317
            |||....:.|...:..:....:||||||:|..|.:..::...:...:.....|.|:.|:....|.
Human   230 TGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIF 294

  Fly   318 CSKEVQEKFIVEAKDVLKEWYGENIQSSP--DLSRVINANNFQRLLGLMK-----SGRVAVGGNY 375
            ..|.:..:|:....:..::| ...|.|.|  .:..:|:..:.:::...:|     ..::..|...
Human   295 VQKSIYSEFLKRFVEATRKW-KVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGV 358

  Fly   376 D--------ASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYV 432
            |        .:..|:.||::.|:|:....|.||||||:..:...:|..:.|:..|..:..|...|
Human   359 DKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATV 423

  Fly   433 FSNSNKLVKEFRRSTTSGGFSSNETIMHCGVD---VLPFGGVGMSGMGRYHGKYGFETFTHKKS 493
            :|::...|....:...||...:|     |.:.   .|||||:..||:||...|..::.||..|:
Human   424 WSSNVGRVHRVAKKLQSGLVWTN-----CWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKT 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	113/454 (25%)
ALDH8A1	NP_072090.1	ALDH_F8_HMSADH	27..485	CDD:143412	113/454 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810