Protein Alignment Aldh-III and ALDH7A1

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001173.2
• Gene: ALDH7A1 / 501
• HGNCID: 877
• Length: 539
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 107/499 - (21%)
• Similarity: 191/499 - (38%)
• Gaps: 110/499 - (22%)

  Fly    67 MANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETE 131
            :|::::|:::||.|:.                               :.||:..||:..:
Human    85 VADYEETVKKAREAWK-------------------------------IWADIPAPKRGEI----- 113

  Fly   132 FMKNDIRHILFQLDEWVQ------SEKPPKSFVNMMDDVQIYND--------------------- 169
                 :|.|...|.|.:|      |.:..|..|..:.:||.|.|
Human   114 -----VRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSER 173

  Fly   170 ----------PFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKYL 224
                      |.|:|.:|.|:|:|:.:.....|.|:..||..:.|.:...:..:..:..:|.|.|
Human   174 SGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVL 238

  Fly   225 DNDCYP-----VVCGGPS-ETAELLNQRFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPC 283
            :::..|     :.|||.. .||...::|.:.:.:||||:|||.:.....:....:.|||||.:..
Human   239 EDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAI 303

  Fly   284 YIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKE------W----- 337
            ...:..|:...|...|:..:...||.|.....:...:.:.::.:...|....:      |
Human   304 IAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVL 368

  Fly   338 YGENIQSSPDLSRVINANNFQRLLGLMKSGRVAVGGN-YDASERFIEPTILVDVKETDPIMEEEI 401
            ||. :.:...:|..:.|....:..|    |.|..||. .|....::||||:..:.....|...|.
Human   369 YGP-LHTKQAVSMFLGAVEEAKKEG----GTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTET 428

  Fly   402 FGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSS--NETIMHCGVD 464
            |.|||.:|..::..:...:.|..::.|...:|:..  |.:.||.....|....  |..|...|.:
Human   429 FAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKD--LGRIFRWLGPKGSDCGIVNVNIPTSGAE 491

  Fly   465 V-LPFGGVGMSGMGRYHGKYGFETFTHKKSC---LGKDLSPLGE 504
            : ..|||...:|.||..|...::.:..:.:|   ..||| ||.:
Human   492 IGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDL-PLAQ 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	106/494 (21%)
ALDH7A1	NP_001173.2	ALDH_F7_AASADH	53..527	CDD:143448	102/489 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900