Protein Alignment Aldh-III and aldh8a1

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001004540.1
• Gene: aldh8a1 / 447801
• ZFINID: ZDB-GENE-040912-3
• Length: 487
• Species: Danio rerio
• Alignment Length: 453
• Identity: 121/453 - (26%)
• Similarity: 188/453 - (41%)
• Gaps: 54/453 - (11%)

  Fly    74 LQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKN-DI 137
            ::.|:.||.....::.:.|.|.|..|....|....|.:.|...|     |...|.   |.:| ||
Zfish    51 VRAAKEAFPDWSAKSPADRSKVLNKLADLIEARLEEFVQAESKD-----QGKTIT---FARNVDI 107

  Fly   138 RHILFQLDEWVQSEKPPKSFVNMMDDVQIYN----DPFGVVLVIGAWNYPLQLLLVPVASAIAAG 198
            ....:....:..|.....:..:.||.:...|    .|.||..:|..||.||.||...:|.|:|.|
Zfish   108 PRSAYNFRFFASSVLHHTNDCSQMDHMGCLNYTIRCPVGVAGLISPWNLPLYLLTWKIAPAVATG 172

  Fly   199 NCVVIKPSEIAANCAKFIADVIPKYLDNDCYP-----VVCGGPSETAELLNQRFD--YIFYTGST 256
            |.||.||||:.:..|..:..:    |:...:|     :|.|......:.|....|  .|.:||||
Zfish   173 NTVVAKPSEMTSVTAWMMCQL----LEEAGFPPGVVNIVFGTGPRAGDALVSHPDVPLISFTGST 233

  Fly   257 RVGKIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKE 321
            ...::|...:..:....:||||||:|..|....||...:...:.....|.|:.|:....|...:.
Zfish   234 ATARLITERSAPHCKKLSLELGGKNPAIIFADADMEQCISTTVRSSFSNQGEICLCTSRIFVERS 298

  Fly   322 VQEKFIVEAKDVLKEWYGENIQSSP--DLSRVINANNFQRL-----LGLMKSGRVAVG------- 372
            |..:|:....:..:.| ...:.|.|  |...:|:..:.|::     |.|.:..:|..|
Zfish   299 VYPEFLTRFVEATRRW-KTGVPSDPSNDNGALISKEHLQKVKGYITLALAEGAQVHCGEGVDKLA 362

  Fly   373 ------GNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIY 431
                  |.|     |:.|||:..||::..:|:||||||:..:...:...:.|...|.....|...
Zfish   363 LPQQNIGGY-----FMLPTIISGVKDSSALMQEEIFGPVTCVTPFDEEEEVISRANNVRYGLSAT 422

  Fly   432 VFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDV-LPFGGVGMSGMGRYHGKYGFETFTHKKS 493
            |:|.....|....|...:|...:|..::.   |: |||||:..||:||..||..:..||..||
Zfish   423 VWSRDVGRVHRVARKLQAGLVWTNCWLVR---DLNLPFGGMKHSGIGREGGKDSYHFFTEVKS 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	121/453 (27%)
aldh8a1	NP_001004540.1	ALDH_F8_HMSADH	27..485	CDD:143412	121/453 (27%)