Protein Alignment Aldh-III and aldh2.1

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_956784.1
• Gene: aldh2.1 / 393462
• ZFINID: ZDB-GENE-040426-1262
• Length: 516
• Species: Danio rerio
• Alignment Length: 462
• Identity: 135/462 - (29%)
• Similarity: 216/462 - (46%)
• Gaps: 53/462 - (11%)

  Fly    62 SESDRMANFDDTLQRARLAFSSG---KTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQ 123
            :|.|: |:.|..::.||.||..|   :..:.|.|...|..|..|.|.....:......|..:|..
Zfish    68 AEGDK-ADVDKAVKAARDAFKLGSPWRRMDASQRGLLLNRLADCIERDAAYLAELETLDNGKPYT 131

  Fly   124 ESLIVETEFMKNDIRHILFQLDEWVQSEKPPKSFVNMMDD---VQIYNDPFGVVLVIGAWNYPLQ 185
            .|..|:...:...:|:.....|:|.....|       :|.   ....::|.||...|..||:||.
Zfish   132 LSFCVDLPMVVKCLRYYAGWADKWEGKTIP-------IDGNYFCYTRHEPIGVCGQIIPWNFPLL 189

  Fly   186 LLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVI-----PKYLDNDCYPVVCG-GPSETAELLN 244
            :..:.:..|:|.||.||:|.:|.....|.:||.:|     |..:.|    :|.| ||:..|.:.:
Zfish   190 MQALKLGPALATGNTVVMKVAEQTPLTALYIASLIKEVGFPAGVVN----IVPGFGPTAGAAIAS 250

  Fly   245 QR-FDYIFYTGSTRVGKIIHAAAN-KYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCG 307
            .. .|.:.:||||.||.:|..|:: ..|...:||||||||..|....:|..||::.......|.|
Zfish   251 HMDVDKVAFTGSTDVGHLIQQASSASNLKNVSLELGGKSPNIILSDANMEEAVEQAHSALFFNQG 315

  Fly   308 QTCIAPDYILCSKEVQEKFI---VE-AKD-VLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSG 367
            |.|.|.......:.:.::|:   || ||: ::.:.:..|.:..|.    ::.:.|:::||.:.||
Zfish   316 QCCCAGTRTFVQESIYDEFVERSVERAKNRIVGDPFDLNTEQGPQ----VDEDQFKKVLGYISSG 376

  Fly   368 R----VAVGGNYDASER--FIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREK 426
            :    ..:.|...|:||  ||:||:..|||:...|..||||||::.|...:|..:.|:..|..:.
Zfish   377 KREGAKLMCGGAPAAERGYFIQPTVFGDVKDDMTIAREEIFGPVMQILKFKSLEEVIERANDSKY 441

  Fly   427 PLVIYVFS-NSNKLVKEFRRSTTSGGFSSNETIMHC----GVDVLPFGGVGMSGMGRYHGKYGFE 486
            .|...||: |.:|      .:..|.|..:....::|    ||.. ||||...||:||..|:||.:
Zfish   442 GLAAAVFTQNIDK------ANYISHGLRAGTVWINCYNVFGVQA-PFGGYKASGIGRELGEYGLD 499

  Fly   487 TFTHKKS 493
            .:|..|:
Zfish   500 IYTEVKT 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	131/452 (29%)
aldh2.1	NP_956784.1	ALDH_F1AB_F2_RALDH1	30..510	CDD:143459	135/462 (29%)