Protein Alignment Aldh-III and aldh3a2a

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_997814.1
• Gene: aldh3a2a / 323653
• ZFINID: ZDB-GENE-040718-74
• Length: 488
• Species: Danio rerio
• Alignment Length: 456
• Identity: 214/456 - (46%)
• Similarity: 310/456 - (67%)
• Gaps: 3/456 - (0%)

  Fly    74 LQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIR 138
            :|:||.||.:|:::::.:|.|||:||.|..:|...:|.:||..||.:....:.:.|...::.:|.
Zfish     8 VQQARKAFLTGRSKSLDYRIKQLKNLSRFIKERAADITNALRKDLYKSANSTQLFEILGLEGEIN 72

  Fly   139 HILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVI 203
            ..:.:|.||.......|:.:.:.|||.:..:|.||||:|||||||:.:.|.|:..||||||.||:
Zfish    73 LAVSKLAEWAAPRPVNKNLLTISDDVFLQPEPLGVVLIIGAWNYPIAVTLQPLVGAIAAGNAVVV 137

  Fly   204 KPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELLNQRFDYIFYTGSTRVGKIIHAAANK 268
            ||||::::.|. :.:::..|||::.|.||.||..||.|||.||||:|||||::.|||::..||:.
Zfish   138 KPSEVSSHTAS-VMELMSLYLDSEMYQVVTGGVPETQELLKQRFDHIFYTGNSTVGKLVMEAASH 201

  Fly   269 YLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDV 333
            :|||.||||||||||||||:.|:|.|.:||.|||.:||||||||||||||...:|::.|.|.:..
Zfish   202 HLTPVTLELGGKSPCYIDKNCDIRIACRRITWGKYLNCGQTCIAPDYILCESSIQDRVIDEIQKC 266

  Fly   334 LKEWYGENIQSSPDLSRVINANNFQRLLGLMKSGRVAVGGNYDASERFIEPTILVDVKETDPIME 398
            :||:|..:.::..|..|:||..:|:|::.|::...||:||:.|.||.:|.||:|.|||....:|:
Zfish   267 IKEFYTIDPKTFEDYGRIINRRHFKRIMALLEGSTVAIGGDCDESECYIAPTVLRDVKPASKVMQ 331

  Fly   399 EEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGV 463
            ||||||||||..|....:||:|||.|||||.:||||:|.|::|:....|:||...:|:.::|..:
Zfish   332 EEIFGPILPIVTVNGLKEAIEFINDREKPLALYVFSSSKKVIKQMISETSSGALLANDCMVHFTL 396

  Fly   464 DVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRK 528
            ..|||||||.||.|||||||.|:..:|.:|||.|.|:.  |.::..||||::..|......||.|
Zfish   397 SDLPFGGVGYSGTGRYHGKYSFDQVSHLRSCLIKKLNM--EAVNQMRYPPHTTEKLRWARVLLLK 459

  Fly   529 R 529
            :
Zfish   460 Q 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	210/440 (48%)
aldh3a2a	NP_997814.1	ALDH_F3AB	5..446	CDD:143450	210/440 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	442	1.000	Domainoid score	I516
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	457	1.000	Inparanoid score	I1556
OMA	1	1.010	-	-		QHG62894
OrthoDB	1	1.010	-	-		D225045at33208
OrthoFinder	1	1.000	-	-		FOG0000656
OrthoInspector	1	1.000	-	-		otm25475
orthoMCL	1	0.900	-	-		OOG6_100557
Panther	1	1.100	-	-	O	PTHR43570
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2145
SonicParanoid	1	1.000	-	-		X395
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910