Protein Alignment Aldh-III and Aldh1b1

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001011975.1
• Gene: Aldh1b1 / 298079
• RGDID: 1306737
• Length: 519
• Species: Rattus norvegicus
• Alignment Length: 518
• Identity: 146/518 - (28%)
• Similarity: 222/518 - (42%)
• Gaps: 72/518 - (13%)

  Fly     8 PHPEA--NGAPIN-----AAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESD 65
            |:||.  |...||     |...:...||     .|.|...||                 ..:|.|
  Rat    32 PNPEIRYNQLFINNEWHDAVSKKTFPTV-----NPTTGEVIG-----------------HVAEGD 74

  Fly    66 RMANFDDTLQRARLAFSSGK--TRNVSFRRKQLENLLRCYEEHENEIISALEA-DLRRPKQESLI 127
            | |:.|..::.||.||..|.  .|..:..|.:|.|.|....|.:...:::||. |..:|.|||.:
  Rat    75 R-ADVDLAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYV 138

  Fly   128 VETEFMKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQI---YNDPFGVVLVIGAWNYPLQLLLV 189
            ::.:.:....|::....|:|.....|       ||....   .::|.||...|..||:||.:...
  Rat   139 LDLDEVIKVYRYLAGWADKWHGKTIP-------MDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGW 196

  Fly   190 PVASAIAAGNCVVIKPSEIAANCAKFIADVI-----PKYLDNDCYPVVCG-GPSETAELL-NQRF 247
            .:|.|:|.||.||:|.:|.....|.::|.:|     |..:.|    ::.| ||:..|.:. :...
  Rat   197 KLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVN----IITGYGPTAGAAIAQHMDV 257

  Fly   248 DYIFYTGSTRVGKIIH-AAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCI 311
            |.:.:||||.||.:|. ||.:..|...|||||||||..:....||..||.:.......|.||.|.
  Rat   258 DKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQCCC 322

  Fly   312 APDYILCSKEVQEKF----IVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLM----KSGR 368
            |.......:.:..:|    :.:||   |...|...:........::...|:::||.:    |.|.
  Rat   323 AGSRTFVEESIYHEFLERTVEKAK---KRKVGNPFELDTQQGPQVDKEQFEKILGYIRLGQKEGA 384

  Fly   369 VAVGGNYDASER--FIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIY 431
            ..:.|.....||  ||:||:..:|::...|..||||||:.|:|..:...:.|:..|.....|...
  Rat   385 KLLCGGERFGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKKIEEVIQRANNTRYGLAAA 449

  Fly   432 VFSNSNKLVKEFRRSTTSGGFSSNE-TIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKS 493
            ||:........|.::..:|....|. .|:.|..   ||||...||.||..|:.|.:.:|..|:
  Rat   450 VFTRDLDKALYFSQALQAGTVWVNTYNIVTCHT---PFGGFKESGNGRELGEDGLKAYTEVKT 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	128/447 (29%)
Aldh1b1	NP_001011975.1	ALDH_F1AB_F2_RALDH1	33..513	CDD:143459	145/517 (28%)