Protein Alignment Aldh-III and Aldh8a1

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_848828.1
• Gene: Aldh8a1 / 237320
• MGIID: 2653900
• Length: 487
• Species: Mus musculus
• Alignment Length: 492
• Identity: 117/492 - (23%)
• Similarity: 195/492 - (39%)
• Gaps: 70/492 - (14%)

  Fly    34 EPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLEN 98
            :|.|..   ::...|.|.:::.|.               .::.||.||.:..:|:...|...|..
Mouse    29 DPSTGE---VYCKVPNSGKEEIEA---------------AVEAAREAFPAWSSRSPQERSLVLNR 75

  Fly    99 LLRCYEEHENEIISALEAD------LRRPKQ--ESLIVETEFMKNDIRHILFQLDEWVQSEKPPK 155
            |....|:...|:..|...|      |.|...  .|::....|..:::.|:         ||....
Mouse    76 LADVLEQSLEELAQAESKDQGKTLTLARTMDIPRSVLNFRFFASSNLHHV---------SECTQM 131

  Fly   156 SFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVI 220
            |.:..|.  .....|.|:..:|..||.||.||...:|.||||||.|:.||||:.:..|....
Mouse   132 SHLGCMH--YTVRTPVGIAGLISPWNLPLYLLTWKIAPAIAAGNTVIAKPSEMTSVTAWMFC--- 191

  Fly   221 PKYLDNDCYP-----VVCGGPSETAELL--NQRFDYIFYTGSTRVGKIIHAAANKYLTPTTLELG 278
             |.||....|     :|.|......|.|  :.....|.:|||....:.|...:..:....:||||
Mouse   192 -KLLDKAGVPPGVINIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELG 255

  Fly   279 GKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEW-YGENI 342
            ||:|..|.:..::...:...:.....|.|:.|:....|...:.:..:|:....:..::| .|...
Mouse   256 GKNPAIIFEDANLEECIPATVRSSFANQGEICLCTSRIFVQRSIYSEFLKRFVEATRKWKVGVPS 320

  Fly   343 QSSPDLSRVINANNFQR-----LLGLMKSGRVAVGGNYD--------ASERFIEPTILVDVKETD 394
            ..|.::..:|:..:.::     |....:..|:..|...|        .:..|:.||::.|:|:..
Mouse   321 DPSANMGALISKAHLEKVRSYVLKAQTEGARILCGEGVDQLSLPLRNQAGYFMLPTVITDIKDES 385

  Fly   395 PIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIM 459
            ..|.||||||:..:...:|..:.|...|:....|...|:|.....:....:...||...:|
Mouse   386 RCMTEEIFGPVTCVVPFDSEEEVITRANSVRYGLAATVWSKDVGRIHRVAKKLQSGLVWTN---- 446

  Fly   460 HCGVD---VLPFGGVGMSGMGRYHGKYGFETFTHKKS 493
             |.:.   .|||||:..||:||...|..::.||..|:
Mouse   447 -CWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKT 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	112/454 (25%)
Aldh8a1	NP_848828.1	ALDH_F8_HMSADH	27..485	CDD:143412	117/492 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810