Protein Alignment Aldh-III and ALDH3B1

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_000685.1
• Gene: ALDH3B1 / 221
• HGNCID: 410
• Length: 468
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 233/451 - (51%)
• Similarity: 315/451 - (69%)
• Gaps: 2/451 - (0%)

  Fly    72 DTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKND 136
            |||:|.|.||.:|:||...||..||:.|.|..:|::..:..||..||.:...||.:.|....:.:
Human     6 DTLRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGE 70

  Fly   137 IRHILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCV 201
            :...|..|..|::.|:.||:....:|...|..:|||:||:|..|||||.|.|||:..|:||||||
Human    71 VTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCV 135

  Fly   202 VIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELLNQRFDYIFYTGSTRVGKIIHAAA 266
            |:|||||:.|..|.:|:|:|:|:|..|:.||.|||.||.:||..||||||:|||.|||||:..||
Human   136 VLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGKIVMTAA 200

  Fly   267 NKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAK 331
            .|:|||.|||||||:|||:|.:.|.:|...|:.|.:..|.||||:||||:|||.|:||:.:...:
Human   201 AKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQ 265

  Fly   332 DVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSGRVAVGGNYDASERFIEPTILVDVKETDPI 396
            ..:..:||::.||||:|.|:||...||||..|:..||||:||..|.|:|:|.||:||||:|.:|:
Human   266 STITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSDESDRYIAPTVLVDVQEMEPV 330

  Fly   397 MEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHC 461
            |:||||||||||.||:|..:||:|||.|||||.:|.||||:::||.....|:||||..|:..||.
Human   331 MQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHM 395

  Fly   462 GVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLL 522
            .:..|||||||.|||||||||:.|:||:|.::||.:  ||..|||::.||||.|.|:..:|
Human   396 TLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLR--SPGMEKLNALRYPPQSPRRLRML 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	230/442 (52%)
ALDH3B1	NP_000685.1	ALDH_F3AB	6..447	CDD:143450	230/442 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	456	1.000	Domainoid score	I495
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H73890
Inparanoid	1	1.050	486	1.000	Inparanoid score	I1445
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62894
OrthoDB	1	1.010	-	-		D225045at33208
OrthoFinder	1	1.000	-	-		FOG0000656
OrthoInspector	1	1.000	-	-		otm51485
orthoMCL	1	0.900	-	-		OOG6_100557
Panther	1	1.100	-	-	O	PTHR43570
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2145
SonicParanoid	1	1.000	-	-		X395
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.910