Protein Alignment Aldh-III and Aldh5a1

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_766120.1
• Gene: Aldh5a1 / 214579
• MGIID: 2441982
• Length: 523
• Species: Mus musculus
• Alignment Length: 457
• Identity: 122/457 - (26%)
• Similarity: 197/457 - (43%)
• Gaps: 71/457 - (15%)

  Fly    80 AFSSGKTRNVSFRRKQLENLLR-CYE---EHENEIISALEADLRRPKQESLIVETEFMKNDIRHI 140
            ||:|.|  .||.:.:.|  ||| .|:   ::::::...:.|:..:|.:|:        :.:|.:.
Mouse    96 AFNSWK--GVSVKERSL--LLRKWYDLMIQNKDDLAKIITAESGKPLKEA--------QGEILYS 148

  Fly   141 LFQLDEWVQSEKPPKSFVNMMDDVQIYND----------------PFGVVLVIGAWNYPLQLLLV 189
            ...| ||...|..           :||.|                |.||..:|..||:|..::..
Mouse   149 ALFL-EWFSEEAR-----------RIYGDIIYTSAKDKRGLVLKQPVGVAAIITPWNFPSAMITR 201

  Fly   190 PVASAIAAGNCVVIKPSEIAANCAKFIADV-----IPKYLDNDCYPVVCGGPSETAELL--NQRF 247
            .|.:|:|||..||:||:|.....|..:|.:     ||..:.| ..|.......|..|:|  :...
Mouse   202 KVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPAGVYN-VIPCSRNKAKEVGEVLCTDPLV 265

  Fly   248 DYIFYTGSTRVGKI-IHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCI 311
            ..|.:||||..||| :|.|||. :...::||||.:|..:..|.::..||...:..|..|.||||:
Mouse   266 SKISFTGSTATGKILLHHAANS-VKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCV 329

  Fly   312 APDYILCSKEVQEKFIVEAKDVLKE--WYGENIQSSPDLSRVINANNFQRLL-----GLMKSGRV 369
            ..:..|..:.:.:.|:.:..:.:|:  ..|...:.......:||....:::.     .:.|...|
Mouse   330 CSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVAKGATV 394

  Fly   370 AVGG-NYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVF 433
            ..|| .:.:...|.|||:|.:|......:.||.|||:.|:...:...:|:...||.|..|..|.:
Mouse   395 VTGGKRHQSGGNFFEPTLLSNVTRDMLCITEETFGPLAPVIKFDKEEEAVAIANAAEVGLAGYFY 459

  Fly   434 SNSNKLVKEFRRSTTSGGFSSNETI---MHCGVDVLPFGGVGMSGMGRYHGKYGFETFTH-KKSC 494
            |.....:.........|....||.:   :.|     |||||..||:||...|||.:.:.. |..|
Mouse   460 SQDPAQIWRVAEQLEVGMVGVNEGLISSVEC-----PFGGVKQSGLGREGSKYGIDEYLEVKYVC 519

  Fly   495 LG 496
            .|
Mouse   520 YG 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	122/457 (27%)
Aldh5a1	NP_766120.1	SSADH	66..516	CDD:188167	119/450 (26%)